DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and LOC100364523

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001316813.1	Gene:	LOC100364523 / 100364523	RGDID:	2320837	Length:	343	Species:	Rattus norvegicus

Alignment Length:	333	Identity:	119/333 - (35%)
Similarity:	181/333 - (54%)	Gaps:	40/333 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   301 FD-KVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELN-ANEMGSAKY--GITEFADMT 361
            || .:|..:.::::::.:.| |..|..::..::.:|:|.||..| .|.:|...|  .|.:|||:|
  Rat    21 FDLSLDVQWQEWKMKYEKLY-SPEEELLKRVVWEENVKKIELHNRENSLGKNTYIMEINDFADLT 84

  Fly   362 SSEYKER-TG-----------LWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGS 414
            ..|:|:. ||           ||:|    |.|.|......:...|||..|||::..||.|:.||.
  Rat    85 DEEFKDMITGITLPINNTMKSLWKR----ALGSSLPNSWYWRDALPKFVDWRKEGYVTHVRVQGR 145

  Fly   415 CGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTT--DSACNGGLMDNAYKAIKDIGGLEYE 477
            |.|||||.|.|.|||....|||:|...|.|.|:||...  :..|.||...||::.:...||||.|
  Rat   146 CNSCWAFPVVGAIEGQMFKKTGKLTPLSVQNLVDCSKPQGNKGCRGGTTYNAFQYVLQNGGLESE 210

  Fly   478 AEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINA--NAMQFYRGGV 540
            |.|||:.|:..|.:|...|..::..||.||: ||..:.:.:...||::.||:.  ::::||:.|:
  Rat   211 ATYPYEGKEGLCRYNPNNSSAKITRFVALPE-NEDVLMDAVATKGPVAAGIHVVHSSLRFYKKGI 274

  Fly   541 SHPWKALCSKKNLDHGVLVVGYGV----SDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRG-DN 600
            .|..|  |: ..::|.|||||||.    :|..|      ||:::||||.|||..||.::.:. :|
  Rat   275 YHEPK--CN-NYVNHAVLVVGYGFEGNETDGNN------YWLIQNSWGERWGLNGYMKIAKDRNN 330

  Fly   601 TCGVSEMA 608
            .||::..|
  Rat   331 HCGIATFA 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	16/59 (27%)
		Peptidase_C1A	395..611	CDD:239068	89/223 (40%)
LOC100364523	NP_001316813.1	Inhibitor_I29	29..87	CDD:214853	16/58 (28%)
LOC100364523	NP_001316813.1	Peptidase_C1A	126..341	CDD:239068	89/223 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910