DRSC/TRiP Functional Genomics Resources

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Protein Alignment rtp and Als2

DIOPT Version :9

Sequence 1:NP_649520.1 Gene:rtp / 40627 FlyBaseID:FBgn0087005 Length:198 Species:Drosophila melanogaster
Sequence 2:NP_001153420.2 Gene:Als2 / 74018 MGIID:1921268 Length:1651 Species:Mus musculus


Alignment Length:213 Identity:55/213 - (25%)
Similarity:80/213 - (37%) Gaps:55/213 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 GHHQQGQ--GQSQYS------------------AGAVKVGGWRYEDASRYIGEWNQRGQKHGIGH 79
            ||.::|:  ||..||                  .|.::.|.......|.:||:| ...:|.|.| 
Mouse  1096 GHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQW-VMDKKAGYG- 1158

  Fly    80 LQFAD---GTRYDGQFQEGLSQGVGCLWFADGAKYEGEFHQGWFHGNGIFWRADGMKYEGEFRGG 141
             .|.|   |.:|.|.:|:.:.||.|.:....|..|||.||.....|||:....|...|||||...
Mouse  1159 -VFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDD 1222

  Fly   142 KIW---GLGLLTFQ--DFTHGFPRNE---------GFFQDCRFMRRRRCPEVVQRAQKCALMARS 192
              |   |.|.||..  |:..|:...|         .:|:...:...:..|:..::....|:.|..
Mouse  1223 --WTLSGKGTLTMPHGDYIEGYFSGEWGSGIKITGTYFKPSLYESDKDKPKAFRKLGNLAVAADE 1285

  Fly   193 Q-------------CEHP 197
            :             ||.|
Mouse  1286 KWRAVFEECWRQLGCESP 1303

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rtpNP_649520.1 COG4642 54..>151 CDD:332236 36/102 (35%)
Als2NP_001153420.2 RCC1 1. /evidence=ECO:0000305 59..108
RCC1_2 93..122 CDD:290274
RCC1 2. /evidence=ECO:0000305 109..167
RCC1 109..165 CDD:278826
RCC1 3. /evidence=ECO:0000305 169..218
RCC1 170..216 CDD:278826
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 425..462
RCC1 4. /evidence=ECO:0000305 519..570
RCC1 521..568 CDD:278826
RCC1 5. /evidence=ECO:0000305 572..621
RCC1 573..619 CDD:278826
RhoGEF 689..873 CDD:295373
PH_alsin 899..1004 CDD:241423
PH 920..998 CDD:278594
COG4642 1043..1182 CDD:226989 24/88 (27%)
MORN 1 1043..1065
MORN 1043..1063 CDD:280628
MORN 2 1066..1088
MORN 3 1094..1116 7/19 (37%)
MORN 1094..1114 CDD:280628 7/17 (41%)
MORN 4 1117..1139 2/21 (10%)
MORN 5 1145..1167 8/24 (33%)
COG4642 1166..>1266 CDD:226989 31/101 (31%)
MORN 6 1169..1191 7/21 (33%)
MORN 7 1192..1214 9/21 (43%)
MORN 8 1215..1238 10/24 (42%)
VPS9 1548..1647 CDD:280383
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4642
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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