Protein Alignment Mms19 and mms-19

DIOPT Version :9

• Sequence 1: NP_649519.1
• Gene: Mms19 / 40626
• FlyBaseID: FBgn0037301
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: NP_504457.2
• Gene: mms-19 / 178935
• WormBaseID: WBGene00016060
• Length: 922
• Species: Caenorhabditis elegans
• Alignment Length: 1062
• Identity: 224/1062 - (21%)
• Similarity: 384/1062 - (36%)
• Gaps: 272/1062 - (25%)

  Fly    16 DQKLVNSATQ-------IAKDLTAKAYDISALAEALGFALSSPDMEERVAGTNLLSAVLIALPQD 73
            ||...:|:||       :.|..|...:..|...:     :.|...|||......:..|:...|.|
 Worm     6 DQNDTDSSTQEWYRLLVVEKSTTLSDFMTSKRTK-----MVSDFPEEREEAIEEIIEVISTFPMD 65

  Fly    74 LLQERQLEFLSTFYMDRLRDHHNVMPAIIDGIDALV-HMKALPRAQIPQILQSFFEHTTCQSQTR 137
            .||:.::..|..::::.:........|:|.|:..|: ..|.||......:::..|:....||..:
 Worm    66 FLQKDEVSLLLNYFINSIESSALTGGAVIRGVHHLILKSKNLPDNFEVSLIRVLFKEGNVQSWAQ 130

  Fly   138 SDRTKLFHIFQYLTENFQDELQAMAGDFVYGLINSIDGERDPRNLDIIFSFMPEFLSTYPLLHLA 202
            .:|...:.|..:..:.....|:.:..||:...:.|:.||||||.|..:||...|..:.:.|....
 Worm   131 KERQLQYEILIWFLKYRLSFLKGLGPDFLATFMKSVSGERDPRCLVHMFSAFLEVSNNFTLGPFT 195

  Fly   203 EEMFEIFACYFPIDFNPSKQDPAAITRDELSKKLTNCLVANNEFAEGTVVLAIEKL--------E 259
            |:|||..|||||::|.|.|.|  .|||:.|:....:|||::..||....:...|||        |
 Worm   196 EDMFETIACYFPVEFKPQKTD--TITREYLAASCASCLVSSPSFAPFCFLFIDEKLNDDDCSDEE 258

  Fly   260 SELLVAKLDSIELLHQAAVKFPP-----SVLEP--------------------HFDQIWQA---L 296
            .|      |.:.||..|..:||.     |::||                    :..|.::|   |
 Worm   259 YE------DVLNLLILAYNRFPAQKKNLSLIEPLIGGIRKIGLNPKNKGEMQKYVSQAFEAVIKL 317

  Fly   297 KTETFPGN-------------DNEE-ILKASL----KALSALLERAAHIPDISHSYQSSILGVIL 343
            .|::...|             |:|. :|:|.:    |||:.|......:||.:
 Worm   318 CTKSSETNSKALDGIVSSIVEDSEPFVLQAEMGLCKKALTLLRSAFKSLPDKN------------ 370

  Fly   344 PHLSDVNQRLFHPATGIALVCVSGDAPYAADKILNSFLLKLQAADASSEQRIKIYYIVSQVYKLS 408
                  ::::|:......|..:.||:..||..       :........|..::...:.|:..:||
 Worm   371 ------SRQIFNQVIAWILNLIQGDSVNAAGN-------RADIVQEGLEYLVEWIQLASEYKELS 422

  Fly   409 ALRGSLQKLDTTIRESVQDDVIASLRLIEQEEFDAKKEDLELQ-KAALSVLNESAPLLNEKQRA- 471
                                 |.:|.:.||..|::.....|.: :.|::.:.|.|.:..|...|
 Worm   423 ---------------------IETLAVFEQSIFESCSRAREFKPREAITAIYECASVYFESDCAS 466

  Fly   472 --LI-----YKALVQLVSHPSIDIDFTTLTVSLGALQPVEVQS--NF--IDVCVRNFEIFSTFVK 525
              ||     |.||. |.:....|.||.:|      |:.:.:.|  ||  :::.:.:.|..|....
 Worm   467 DELISQCRSYIALA-LRTPIDTDSDFQSL------LKLIRIYSSKNFDQVEIILADNETNSWNAM 524

  Fly   526 RKIYTNLLPLMPQIAFTQR-------ILDLVMTQTFNDTTAEPVRLLALEALNKLLLLADQRFIV 583
            :     :||::..|:.:||       |:| .:..|.:.:|.....:..::.:.|
 Worm   525 K-----VLPVLCAISCSQRWNLLKNKIVD-ELGSTISSSTEISYLICYVQMMEK----------- 572

  Fly   584 DVQQESNLLHKLIELGQ----KT---EGLSMQSLEQIAGALSRITQQLPLSEQSAIVSEYLPGLN 641
             .:::..|.|:..|:.:    ||   |.:|:..|.|....|...........|:....:.|.|
 Worm   573 -CKKDPQLFHQQFEVFESVLYKTDCNEPVSVSYLMQSISLLLSEDDHQKFMNQTTTRYQSLEG-- 634

  Fly   642 LSQSADLYITKGLLGYLHKDITLDDHFERLLTDLTQLSLNSDNEQLRVIAHHLLCSMVNKMESNP 706
              .|.|.:..|..|.||....|.|      |..:..|.|..     |.| ..|..::.|:...|.
 Worm   635 --SSLDNFNQKYRLAYLQNKNTND------LKTIANLKLPE-----RTI-RQLFFAICNREAENE 685

  Fly   707 ANLRKVKKITEQLKVAIKKGDVRAVEILAWVGKGLVVAGFDEAADVVGDLSDLLKHPSLSTAA-- 769
            .|    .:|.||..:|    :::| ::|.            .|.:.:......|.:.|.||.:
 Worm   686 NN----SEIPEQHHIA----EIKA-KLLR------------NAPNSLSAFEQFLTNISGSTESPF 729

  Fly   770 --ALGFDIIAAEYPELDLPVVKFLYKQKLFHTIM----------GKMGSKLANYCVHHLKAFVYV 822
              .|.||...:............|::|::|..|:          |.....|.....|.|...|
 Worm   730 EYLLDFDSFDSNPDRCRYETASPLWRQRIFCQIVPIFKRKFEEPGSQKHVLVEMLPHLLTFAV-- 792

  Fly   823 LKATPQAVIKLNIEQLGPLLFKSLEEHNEAQSLCIALGICEKFVAQQDTYFQGHLAHLIPSCLEL 887
                             ||.|:.|:     :...:.|.:..:.:..:|. ...|:...||..|.:
 Worm   793 -----------------PLDFQQLK-----KQFAMLLPVLIQTIGMEDV-IPSHVTRTIPMFLTI 834

  Fly   888 S------------KYKAQHT---------MQVRIAALQLLYDVTKYPTFVLLPHKVDVTLALAAA 931
            |            ||....|         ::..:..|.:|  ..:.|...|......|..::...
 Worm   835 SEPLQPKDLGTVVKYLCSITRDNDSNMTNLEDALNGLNIL--ARRQPPKSLHSEVPLVVTSINKI 897

  Fly   932 LDDPKRLVRNTAVKARNAWYLV 953
            |...|||:|..|...:|.|.:|
 Worm   898 LGHKKRLLRMMAADVKNNWEMV 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mms19	NP_649519.1	MMS19_N	44..301	CDD:291186	77/293 (26%)
		MMS19_C	<658..887	CDD:289245	45/242 (19%)
mms-19	NP_504457.2	MMS19_N	60..296	CDD:373098	68/243 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156169
Domainoid	1	1.000	97	1.000	Domainoid score	I4575
eggNOG	1	0.900	-	-		E1_KOG1967
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402058at33208
OrthoFinder	1	1.000	-	-		FOG0003902
OrthoInspector	1	1.000	-	-		oto19537
orthoMCL	1	0.900	-	-		OOG6_102900
Panther	1	1.100	-	-	LDO	PTHR12891
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R725
SonicParanoid	1	1.000	-	-		X2685
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.870