DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vps37B and vps37bb

DIOPT Version :9

Sequence 1:	NP_001246926.1	Gene:	Vps37B / 40624	FlyBaseID:	FBgn0037299	Length:	214	Species:	Drosophila melanogaster
Sequence 2:	NP_001025385.1	Gene:	vps37bb / 566797	ZFINID:	ZDB-GENE-050913-110	Length:	231	Species:	Danio rerio

Alignment Length:	225	Identity:	67/225 - (29%)
Similarity:	103/225 - (45%)	Gaps:	49/225 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 EELKELLNDDDKL-------DEKVDEVLQVLRTQKTSVFEDNRSRAERNIEREPQIIELRGQLAE 76
            |::.|:|.|::||       .||     |.::..|..:...|||.||.|:..:|.:...:.||.:
Zfish    17 EQIMEILEDEEKLTSIARDSGEK-----QEMQQSKELMMASNRSLAEMNLNLQPDLDHQKIQLTK 76

  Fly    77 LSEDGRTRCSSVQEKLSQLKEKS-GGVGLETALALLQTAASESEEQTEEMVKKFNDSDIGVEDFL 140
                 |..|.....:..||:..: |...|:|.||||||..::.||:||.|...|.|..:.::.|:
Zfish    77 -----RYCCLQELHESYQLRRSTLGSSSLDTLLALLQTEGAKIEEETENMADSFLDGSMPLDSFI 136

  Fly   141 DAFLPIRRTMHLRRLKAEKMQELMRK-------------------QRQG--------PGPNTSLP 178
            |.:...|:..||||:|.:|:||::.|                   ||..        |....|..
Zfish   137 DDYQSKRKLAHLRRVKIDKLQEMLLKGIHLPQGSSNEHQESLNSFQRLSNGSPAHVKPTSQASAS 201

  Fly   179 AYGNVPSSGFYPASGGSAPYPIMGPLMPMP 208
            .|.|:|::  .|:|..|| || .||...:|
Zfish   202 PYANLPNA--MPSSYSSA-YP-QGPGSALP 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps37B	NP_001246926.1	PABP	<16..42	CDD:295409	9/29 (31%)
Vps37B	NP_001246926.1	Mod_r	19..153	CDD:284587	43/141 (30%)
vps37bb	NP_001025385.1	Mod_r	15..149	CDD:284587	43/141 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595854
Domainoid	1	1.000	84	1.000	Domainoid score	I8181
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11649
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45937
OrthoDB	1	1.010	-	-		D1197293at2759
OrthoFinder	1	1.000	-	-		FOG0003711
OrthoInspector	1	1.000	-	-		otm25656
orthoMCL	1	0.900	-	-		OOG6_107562
Panther	1	1.100	-	-	O	PTHR13678
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.860