DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vps37B and vps37ba

DIOPT Version :9

Sequence 1:	NP_001246926.1	Gene:	Vps37B / 40624	FlyBaseID:	FBgn0037299	Length:	214	Species:	Drosophila melanogaster
Sequence 2:	NP_001093466.1	Gene:	vps37ba / 559483	ZFINID:	ZDB-GENE-060526-254	Length:	288	Species:	Danio rerio

Alignment Length:	230	Identity:	67/230 - (29%)
Similarity:	108/230 - (46%)	Gaps:	39/230 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ELKELLNDDDKLDEKVDEVLQV--LRTQKTSVFEDNRSRAERNIEREPQIIELRGQLAELSEDGR 82
            :|.|||.|||||::.:||..::  |:..|.:...:||..||:|:..:|::...:.:|.......:
Zfish    15 QLNELLEDDDKLNKFIDESEEIKGLQQNKETTLANNRFLAEQNLLLQPKLDHQKNELTRRYRGLQ 79

  Fly    83 TRCSSVQEKLSQLKEKSGGVGLETALALLQTAASESEEQTEEMVKKFNDSDIGVEDFLDAFLPIR 147
            ....:.|.:.|.|.::.|...|:|.|||||...::.||:||.:...|.|....::.|:|.:...|
Zfish    80 ELYEAYQLRKSTLDDRLGNTPLDTLLALLQAEGAKIEEETENLADAFLDGAAPLDTFIDDYQSKR 144

  Fly   148 RTMHLRRLKAEKMQELMRKQRQGPGPNTSLPAYG-NVPSSGFYPA------SGGSAPYPIMGPLM 205
            :..||||:|.||:||::.|....| |....|:.. ::||.   ||      :|...|.|...|.:
Zfish   145 KLAHLRRVKIEKLQEMVLKGHHMP-PAAPPPSRAQDLPSR---PAALNREVNGSPMPMPRRAPPL 205

  Fly   206 P--------------------------MPPPSRPY 214
            |                          |.||:.||
Zfish   206 PPVKESPQPAPTTAISYPPTSPFPSPSMIPPTSPY 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps37B	NP_001246926.1	PABP	<16..42	CDD:295409	11/23 (48%)
Vps37B	NP_001246926.1	Mod_r	19..153	CDD:284587	41/134 (31%)
vps37ba	NP_001093466.1	Mod_r	12..150	CDD:284587	41/134 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595853
Domainoid	1	1.000	84	1.000	Domainoid score	I8181
eggNOG	1	0.900	-	-		E1_KOG3270
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11649
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45937
OrthoDB	1	1.010	-	-		D1197293at2759
OrthoFinder	1	1.000	-	-		FOG0003711
OrthoInspector	1	1.000	-	-		otm25656
orthoMCL	1	0.900	-	-		OOG6_107562
Panther	1	1.100	-	-	O	PTHR13678
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5541
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.750