Protein Alignment Vps37B and VPS37C

DIOPT Version :9

• Sequence 1: NP_001246926.1
• Gene: Vps37B / 40624
• FlyBaseID: FBgn0037299
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_060436.4
• Gene: VPS37C / 55048
• HGNCID: 26097
• Length: 355
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 76/327 - (23%)
• Similarity: 119/327 - (36%)
• Gaps: 132/327 - (40%)

  Fly    19 EELKELLNDDDKLDEKVDE--VLQVLRTQKTSVFEDNRSRAERNIEREPQIIELRGQLAELSEDG 81
            :||:||.||.:.:|:...|  .:|.|:.::......|||.||||:|.:..:...|..|::..::.
Human    10 QELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEISRSNLSDRYQEL 74

  Fly    82 RTRCSSVQEKLSQLKEKSGGVGLETALALLQTAASESEEQTEEMVKKFNDSDIGVEDFLDAFLPI 146
            |......||:.::|::.|..:...|.|.|||....:.||::|.|.:||.:.::.:|.||:.|..:
Human    75 RKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEVPLETFLENFSSM 139

  Fly   147 RRTMHLRRLKAEKMQELMRKQR----------------------QG--------PGPNTSLPAY- 180
            |...||||::.||:||::||.|                      ||        |.|..::|.|
Human   140 RMLSHLRRVRVEKLQEVVRKPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYP 204

  Fly   181 ----------------------------------------------------------------- 180
                                                                             
Human   205 LPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPR 269

  Fly   181 -------------------GNVPSSGF-----YPASGGSAPYPIM----------GPLMPMPPPS 211
                               |..||.|:     |||:||..||||.          .|.:|:.||.
Human   270 PGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPY 334

  Fly   212 RP 213
            .|
Human   335 PP 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps37B	NP_001246926.1	PABP	<16..42	CDD:295409	9/24 (38%)
		Mod_r	19..153	CDD:284587	42/135 (31%)
VPS37C	NP_060436.4	Mod_r	5..146	CDD:284587	42/135 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	159..355		26/178 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159647
Domainoid	1	1.000	85	1.000	Domainoid score	I8171
eggNOG	1	0.900	-	-		E1_KOG3270
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	106	1.000	Inparanoid score	I4942
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1197293at2759
OrthoFinder	1	1.000	-	-		FOG0003711
OrthoInspector	1	1.000	-	-		otm40312
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13678
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5541
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.890