Protein Alignment Vps37B and VPS37D

DIOPT Version :9

• Sequence 1: NP_001246926.1
• Gene: Vps37B / 40624
• FlyBaseID: FBgn0037299
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_001071089.1
• Gene: VPS37D / 155382
• HGNCID: 18287
• Length: 251
• Species: Homo sapiens
• Alignment Length: 201
• Identity: 58/201 - (28%)
• Similarity: 100/201 - (49%)
• Gaps: 12/201 - (5%)

  Fly    20 ELKELLNDDDKLDE--KVDEVLQVLRTQKTSVFEDNRSRAERNIEREPQIIELRGQLAELSEDGR 82
            :|::||.|:.|||.  ::....|.|:.::.:....|.:.|:.|:...|::...|..||...::.|
Human    26 QLRDLLQDEPKLDRIVRLSRKFQGLQLEREACLASNYALAKENLALRPRLEMGRAALAIKYQELR 90

  Fly    83 TRCSSVQEKLSQLKEKSGGVGLETALALLQTAASESEEQTEEMVKKFNDSDIGVEDFLDAFLPIR 147
            ....:..:||.:|:|.........||..||....|:|::.||.:::....:..:|.||.||...|
Human    91 EVAENCADKLQRLEESMHRWSPHCALGWLQAELEEAEQEAEEQMEQLLLGEQSLEAFLPAFQRGR 155

  Fly   148 RTMHLRRLKAEKMQELMRKQRQG--PGPNTSLPAYGNVPSSGFYPASGGSAPYPIMGPLMP--MP 208
            ...||||.:|||:|||:|::.:.  |.|.::.....:.|::...|......|     |.:|  :|
Human   156 ALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGP-----PAVPRSLP 215

  Fly   209 P-PSRP 213
            | .|||
Human   216 PLDSRP 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps37B	NP_001246926.1	PABP	<16..42	CDD:295409	8/23 (35%)
		Mod_r	19..153	CDD:284587	36/134 (27%)
VPS37D	NP_001071089.1	Mod_r	22..165	CDD:399880	39/138 (28%)
		pneumo_PspA	<138..>248	CDD:411490	29/89 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..251		12/53 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159645
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3270
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40312
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13678
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.800