DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sccpdh1 and sccpdha.1

DIOPT Version :9

Sequence 1:	NP_649517.1	Gene:	Sccpdh1 / 40623	FlyBaseID:	FBgn0037298	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001002359.1	Gene:	sccpdha.1 / 436632	ZFINID:	ZDB-GENE-040718-51	Length:	427	Species:	Danio rerio

Alignment Length:	436	Identity:	183/436 - (41%)
Similarity:	260/436 - (59%)	Gaps:	38/436 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VIIFGASGFTGKYTVFEAVTVLR--------GLRWGIAGRNREKLEAVLKEMGAK-AKKDL-SQV 62
            :||||||||||::.|.|   |.|        .|:|.:|||::.|||.|:::..|. .|.:| ::|
Zfish    14 IIIFGASGFTGQFVVEE---VSRCASEGPKGSLKWAVAGRSKPKLEKVIEQAAANLGKPELKTEV 75

  Fly    63 PIFIADVNDQASLLEMAKKCRIVVNTAGPYRFHGENVVKCCIESGTHHVDVSGEPQYMETMQLRY 127
            .|.:|||:||.||..|.|:..||::..|||||.||.|||.|:|:|.|.:|:|||||::|.|||.|
Zfish    76 DIIVADVSDQESLAAMCKQAVIVLSCVGPYRFFGEPVVKSCVENGAHCLDISGEPQFLEGMQLNY 140

  Fly   128 DQLAREKGVYVVSACGFDSIPADMGVVFVEKNFDGVVNSVETFLETGIKEGGSGGGTAGLNYGTW 192
            ...|.:||||:|.:||||||||||||::....|.|.:.:|::||..     |||...:.||.|||
Zfish   141 HDQAADKGVYIVGSCGFDSIPADMGVIYTRDQFKGTLTAVDSFLTL-----GSGPEGSCLNDGTW 200

  Fly   193 ESAVYGLAHSDELRGIRKQIYPQRLPRFYPFLKPRPLVFRSTEVDKVCLPFPGSDRSVVMRSQRF 257
            :|.:||||...:|:.:||:...:.||...|.:|.|.|:|.|:||.:..:||.|:|.|||.|:||:
Zfish   201 QSVIYGLADKGKLKSLRKKFGHKPLPVVGPKIKRRGLLFYSSEVQQYAIPFIGTDPSVVKRTQRY 265

  Fly   258 LYDQDKKRPVQMQAYVGFSSWLVAGGV------IFFATIFGLLSKFKLGRTLLLNYPGLFSGGLA 316
            |:::..:.|||..||.|.      ||:      :....:|.||:....||.||:.||..||.|..
Zfish   266 LHEELNETPVQYGAYAGI------GGISNVFKFLISGFMFCLLALCSCGRKLLIKYPEFFSFGFF 324

  Fly   317 SRSGPSEESMERTYFKMTFKASGWLKSDRLAESSNQYTESPTKTLMVRVSGMNPGYGATCVAVLS 381
            |..||:::.:|...|.:.|...|:.|....::.      .|...:...|.|...||..|.:|::.
Zfish   325 STEGPTKKQIEDASFHILFFGDGYTKGQDPSKG------KPNGKIRTEVKGPEAGYVTTPIAMVQ 383

  Fly   382 AALTILRESDKMPSTGGVLPPAAAFSKTGLISELEKHDHGIKFEIL 427
            ||:|:|.|.|.:|.||||..|.|.|:||.||..|.|  |||:|.::
Zfish   384 AAITMLNEPDSLPQTGGVYTPGATFAKTTLIKRLNK--HGIEFSVI 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sccpdh1	NP_649517.1	COG3268	7..426	CDD:225807	183/433 (42%)
Sccpdh1	NP_649517.1	Sacchrp_dh_NADP	8..139	CDD:281434	69/140 (49%)
sccpdha.1	NP_001002359.1	COG3268	10..424	CDD:225807	182/431 (42%)
sccpdha.1	NP_001002359.1	Sacchrp_dh_NADP	14..152	CDD:281434	69/140 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590395
Domainoid	1	1.000	202	1.000	Domainoid score	I2937
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9334
Inparanoid	1	1.050	332	1.000	Inparanoid score	I2409
OMA	1	1.010	-	-		QHG56565
OrthoDB	1	1.010	-	-		D302978at33208
OrthoFinder	1	1.000	-	-		FOG0002586
OrthoInspector	1	1.000	-	-		mtm6482
orthoMCL	1	0.900	-	-		OOG6_101495
Panther	1	1.100	-	-	LDO	PTHR12286
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4081
SonicParanoid	1	1.000	-	-		X1697
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.900