Protein Alignment CG1116 and RGP1

DIOPT Version :10

• Sequence 1: NP_730894.2
• Gene: CG1116 / 40622
• FlyBaseID: FBgn0037297
• Length: 443
• Species: Drosophila melanogaster
• Sequence 2: NP_001073965.2
• Gene: RGP1 / 9827
• HGNCID: 21965
• Length: 391
• Species: Homo sapiens
• Alignment Length: 447
• Identity: 156/447 - (34%)
• Similarity: 225/447 - (50%)
• Gaps: 81/447 - (18%)

  Fly     1 MIEIKAKLLRADSAIYATGERVQCLIEFTHKVFSDEPAASQAVHNANEARSQENLAWASAQLHCY 65
            |||:.|:|.|  ..::..||.::|::..|:.:   .|.|:.|        |.|.|||||||:||.
Human     1 MIEVVAELSR--GPVFLAGEALECVVTVTNPL---PPTATSA--------SSEALAWASAQIHCQ 52

  Fly    66 RKTSYSTSA---GDRAAELTEMIGRTALDAVTQAPGEVIVATKPKILFCDLRLQPGETKMYFFNE 127
            ...|.|..|   .|.:....:...:|.........|:.|::|.||||||||||.|||:|.|.::|
Human    53 FHASESRVALPPPDSSQPDVQPDSQTVFLPHRGERGQCILSTPPKILFCDLRLDPGESKSYSYSE 117

  Fly   128 FIPRDGPPTYRGHNIRYFYKITIATQRVKSKVQTLAVPIRVLPIPIISRPDELPVTVETNEELAP 192
            .:|.:|||::||.:::|.||:||..|||.|.:..|.||:|||.:..:.     .|....:|.:||
Human   118 VLPIEGPPSFRGQSVKYVYKLTIGCQRVNSPITLLRVPLRVLVLTGLQ-----DVRFPQDEAVAP 177

  Fly   193 TNPFLE-----KREISELEISWHHLKNVTARRAPKFYRISNKRGFVGRFCLFKPAYKLGEDIVGS 252
            ::||||     |::....|::...|...|:.|:...|.||:.||.||.|.:||..|:||||:||:
Human   178 SSPFLEEDEGGKKDSWLAELAGERLMAATSCRSLHLYNISDGRGKVGTFGIFKSVYRLGEDVVGT 242

  Fly   253 LDFDPGVNPRKVRCVQFSVKLQQQELSIRPQPVQNHQLQSQSSTGDDVSSMNSFDMASIASGVLA 317
            |:...|.    |.|:||||.||.:|   |.||      :.|...|              |.||
Human   243 LNLGEGT----VACLQFSVSLQTEE---RVQP------EYQRRRG--------------AGGV-- 278

  Fly   318 DNLHKSATSASSKVKEAPEPTGKLSTISTSHQVCYATLQTQVVVPIPLHVTPTFRTDLVDVRWRL 382
                               |:....|.:...:.|..|.:|...:||||..||.|.|.:|.::|||
Human   279 -------------------PSVSHVTHARHQESCLHTTRTSFSLPIPLSSTPGFCTAIVSLKWRL 324

  Fly   383 HFEFVTT-----TLIDFGIPNPESGELKAPSEMPVETMVWNLPVTVYAANP-LQIYA 433
            ||||||:     .|:. .:..||......|.::||:|..|:||:.|...:| |..||
Human   325 HFEFVTSREPGLVLLP-PVEQPEPTTWTGPEQVPVDTFSWDLPIKVLPTSPTLASYA 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1116	NP_730894.2	Rgp1	<101..388	CDD:430181	109/291 (37%)
RGP1	NP_001073965.2	Rgp1	<91..330	CDD:430181	109/291 (37%)