DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1116 and Rgp1

DIOPT Version :9

Sequence 1:	NP_730894.2	Gene:	CG1116 / 40622	FlyBaseID:	FBgn0037297	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	XP_038966938.1	Gene:	Rgp1 / 313493	RGDID:	1311757	Length:	417	Species:	Rattus norvegicus

Alignment Length:	448	Identity:	159/448 - (35%)
Similarity:	227/448 - (50%)	Gaps:	83/448 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIEIKAKLLRADSAIYATGERVQCLIEFTHKVFSDEPAASQAVHNANEARSQENLAWASAQLHCY 65
            |||:.|:|.|  ..::..||.::|::..|:.:   .|.|:.|        |.|.|||||||:||.
  Rat    27 MIEVVAELSR--GPVFLAGEALECVVTVTNPL---PPTATSA--------SSEALAWASAQIHCQ 78

  Fly    66 RKTSYSTSA---GDRAAELTEMIGRTALDAVTQAPGEVIVATKPKILFCDLRLQPGETKMYFFNE 127
            ...|.|..|   .|.:....:...:|.........|:.|::|.||||||||||.|||:|.|.::|
  Rat    79 FHASESRVALPPPDSSQPDVQPDSQTVFLPHRGERGQCILSTPPKILFCDLRLDPGESKSYSYSE 143

  Fly   128 FIPRDGPPTYRGHNIRYFYKITIATQRVKSKVQTLAVPIRVLPIPIISRPDELPVTVETNEELAP 192
            .:|.:|||::||.:::|.||:||..|||.|.:..|.||:|||.:..:.     .|....:|.:||
  Rat   144 VLPTEGPPSFRGQSVKYVYKLTIGCQRVNSPITLLRVPLRVLVLTGLQ-----DVHFPQDEAVAP 203

  Fly   193 TNPFLE-----KREISELEISWHHLKNVTARRAPKFYRISNKRGFVGRFCLFKPAYKLGEDIVGS 252
            ::||||     |::....|::...|...|:.|:...|.||:.||.||.|.:||..|:||||:||:
  Rat   204 SSPFLEEDDSGKKDSWLAELAGERLMAATSCRSLHLYNISDGRGKVGTFGIFKSVYRLGEDVVGT 268

  Fly   253 LDFDPGVNPRKVRCVQFSVKLQQQELSIRPQPVQNHQLQSQSSTGDDVSSMNSFDMASIASGVLA 317
            |:...|.    |.|:||||.||.:|   |.||    :.|.:..||             :|..|
  Rat   269 LNLGEGT----VACLQFSVSLQTEE---RVQP----EYQRRRGTG-------------VAPSV-- 307

  Fly   318 DNLHKSATSASSKVKEAPEPTGKLSTISTSHQ-VCYATLQTQVVVPIPLHVTPTFRTDLVDVRWR 381
                       |.|..|            .|| .|..|.:|...:||||..||.|.|.:|.::||
  Rat   308 -----------SHVTHA------------RHQESCLHTTRTSFSLPIPLCSTPGFCTAIVSLKWR 349

  Fly   382 LHFEFVTT-----TLIDFGIPNPESGELKAPSEMPVETMVWNLPVTVYAANP-LQIYA 433
            |||||||:     .|:. .:..||......|.::||:|..|:||:.|...:| |..||
  Rat   350 LHFEFVTSREPGLVLLP-PLEQPEPATWTGPEQVPVDTFSWDLPIKVLPTSPTLVSYA 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1116	NP_730894.2	Rgp1	<101..388	CDD:285895	112/292 (38%)
Rgp1	XP_038966938.1	Rgp1	<117..357	CDD:400883	113/293 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352979
Domainoid	1	1.000	92	1.000	Domainoid score	I7494
eggNOG	1	0.900	-	-		E1_KOG4469
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8863
Inparanoid	1	1.050	218	1.000	Inparanoid score	I3490
OMA	1	1.010	-	-		QHG48632
OrthoDB	1	1.010	-	-		D398202at33208
OrthoFinder	1	1.000	-	-		FOG0005628
OrthoInspector	1	1.000	-	-		oto95647
orthoMCL	1	0.900	-	-		OOG6_104371
Panther	1	1.100	-	-	LDO	PTHR12507
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5274
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770