DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1116 and Rgp1

DIOPT Version :9

Sequence 1:	NP_730894.2	Gene:	CG1116 / 40622	FlyBaseID:	FBgn0037297	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_766454.1	Gene:	Rgp1 / 242406	MGIID:	1915956	Length:	391	Species:	Mus musculus

Alignment Length:	448	Identity:	159/448 - (35%)
Similarity:	227/448 - (50%)	Gaps:	83/448 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIEIKAKLLRADSAIYATGERVQCLIEFTHKVFSDEPAASQAVHNANEARSQENLAWASAQLHCY 65
            |||:.|:|.|  ..::..||.::|::..|:.:   .|.|:.|        |.|.|||||||:||.
Mouse     1 MIEVVAELSR--GPVFLAGEALECVVTVTNPL---PPTATSA--------SSEALAWASAQIHCQ 52

  Fly    66 RKTSYSTSA---GDRAAELTEMIGRTALDAVTQAPGEVIVATKPKILFCDLRLQPGETKMYFFNE 127
            ...|.|..|   .|.:....:...:|.........|:.|::|.||||||||||.|||:|.|.::|
Mouse    53 FHASESRVALPPPDSSQPDVQPDSQTVFLPHRGERGQCILSTPPKILFCDLRLDPGESKSYSYSE 117

  Fly   128 FIPRDGPPTYRGHNIRYFYKITIATQRVKSKVQTLAVPIRVLPIPIISRPDELPVTVETNEELAP 192
            .:|.:|||::||.:::|.||:||..|||.|.:..|.||:|||.:..:.     .|....:|.:||
Mouse   118 VLPTEGPPSFRGQSVKYVYKLTIGCQRVNSPITLLRVPLRVLVLTGLQ-----DVHFPQDEAVAP 177

  Fly   193 TNPFLE-----KREISELEISWHHLKNVTARRAPKFYRISNKRGFVGRFCLFKPAYKLGEDIVGS 252
            ::||||     |::....|::...|...|:.|:...|.||:.||.||.|.:||..|:||||:||:
Mouse   178 SSPFLEEDDSGKKDSWLAELAGERLMAATSCRSLHLYNISDGRGKVGTFGIFKSVYRLGEDVVGT 242

  Fly   253 LDFDPGVNPRKVRCVQFSVKLQQQELSIRPQPVQNHQLQSQSSTGDDVSSMNSFDMASIASGVLA 317
            |:...|.    |.|:||||.||.:|   |.||    :.|.:..||             :|..|
Mouse   243 LNLGEGT----VACLQFSVSLQTEE---RVQP----EYQRRRGTG-------------VAPSV-- 281

  Fly   318 DNLHKSATSASSKVKEAPEPTGKLSTISTSHQ-VCYATLQTQVVVPIPLHVTPTFRTDLVDVRWR 381
                       |.|..|            .|| .|..|.:|...:||||..||.|.|.:|.::||
Mouse   282 -----------SHVTHA------------RHQESCLHTTRTSFSLPIPLCSTPGFCTAIVSLKWR 323

  Fly   382 LHFEFVTT-----TLIDFGIPNPESGELKAPSEMPVETMVWNLPVTVYAANP-LQIYA 433
            |||||||:     .|:. .:..||......|.::||:|..|:||:.|...:| |..||
Mouse   324 LHFEFVTSREPGLVLLP-PLEQPEPATWTGPEQVPVDTFSWDLPIKVLPTSPTLVSYA 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1116	NP_730894.2	Rgp1	<101..388	CDD:285895	112/292 (38%)
Rgp1	NP_766454.1	Rgp1	<91..331	CDD:370091	113/293 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849363
Domainoid	1	1.000	92	1.000	Domainoid score	I7641
eggNOG	1	0.900	-	-		E1_KOG4469
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8863
Inparanoid	1	1.050	218	1.000	Inparanoid score	I3567
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48632
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005628
OrthoInspector	1	1.000	-	-		oto92079
orthoMCL	1	0.900	-	-		OOG6_104371
Panther	1	1.100	-	-	LDO	PTHR12507
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4045
SonicParanoid	1	1.000	-	-		X5274
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790