Protein Alignment Prosbeta2R2 and PSMB10

DIOPT Version :10

• Sequence 1: NP_649515.3
• Gene: Prosbeta2R2 / 40621
• FlyBaseID: FBgn0037296
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_002792.1
• Gene: PSMB10 / 5699
• HGNCID: 9538
• Length: 273
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 97/261 - (37%)
• Similarity: 151/261 - (57%)
• Gaps: 13/261 - (4%)

  Fly    16 PFLCGPSGFTFDNCLRNKQLKE--NGLEEPNSFTTGTTVVGIVFDGGVIIGAESRATSGGIVFSK 78
            |.|....||:|:||.||..|:.  .||:.|::..||||:.|:||..|||:||::|||:..:|..|
Human     4 PALEPRGGFSFENCQRNASLERVLPGLKVPHARKTGTTIAGLVFQDGVILGADTRATNDSVVADK 68

  Fly    79 TCRKIIELQANIFAAGAGTARDTKALVELTRAQLELHRMNTGFRKVPVCCANQMIRQLLFRFNGN 143
            :|.||..:...|:..|||.|.|.:....:..:::|||.::|| |:..|....:::||.|||:.|:
Human    69 SCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTG-REPRVATVTRILRQTLFRYQGH 132

  Fly   144 IDADMIIGGADNTGAHLFCTRSDGSTDTAPFTSIGSGYQVSMSILESRWSEDLSEESACALACDA 208
            :.|.:|:||.|.||..|:.....||....|||::|||...::::||.|:..:::.|:|..|..:|
Human   133 VGASLIVGGVDLTGPQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEA 197

  Fly   209 VAAGMKNDLCSGGKVSLCVVRCDFSVQWPEQLPRQV-----PPTRTYRLSPKPGRTTILSTLVHP 268
            |.||:..||.|||.|..||:     .:...:|.|.:     |..|:.|....||.|.:|:..|.|
Human   198 VTAGILGDLGSGGNVDACVI-----TKTGAKLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKP 257

  Fly   269 V 269
            :
Human   258 L 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R2	NP_649515.3	proteasome_beta_type_7	50..239	CDD:239732	71/188 (38%)
PSMB10	NP_002792.1	proteasome_beta_type_7	40..227	CDD:239732	72/192 (38%)
		Pr_beta_C	231..267	CDD:463597	9/28 (32%)