Protein Alignment Prosbeta2R2 and PSMA5

DIOPT Version :10

• Sequence 1: NP_649515.3
• Gene: Prosbeta2R2 / 40621
• FlyBaseID: FBgn0037296
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_002781.2
• Gene: PSMA5 / 5686
• HGNCID: 9534
• Length: 241
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 53/200 - (26%)
• Similarity: 80/200 - (40%)
• Gaps: 36/200 - (18%)

  Fly    13 DRSPFLCGPSGFTFDNCLRNKQLKENGLEEPNSFTTGTTVVGIVFDGGVIIGAESRATSGGIVFS 77
            ||......|.|..|.        .|..:|   :...|:|.:||....||.:..|.|.|| .::..
Human     9 DRGVNTFSPEGRLFQ--------VEYAIE---AIKLGSTAIGIQTSEGVCLAVEKRITS-PLMEP 61

  Fly    78 KTCRKIIELQANIFAAGAGTARDTKALVELTRAQLELHRMNTGFRKVPVCCANQMIRQLLFRFNG 142
            .:..||:|:.|:|..|.:|...|.|.|::..|.:.:.|.. |....:.|....|.:..|..:| |
Human    62 SSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWF-TYNETMTVESVTQAVSNLALQF-G 124

  Fly   143 NIDAD-----------MIIGGADNTGAHLF----------C-TRSDGSTDTAPFTSIGSGYQVSM 185
            ..|||           ::.||.|..|..||          | .|:.||......:|:...|..||
Human   125 EEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSM 189

  Fly   186 SILES 190
            ::.|:
Human   190 TLKEA 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R2	NP_649515.3	proteasome_beta_type_7	50..239	CDD:239732	45/162 (28%)
PSMA5	NP_002781.2	proteasome_alpha_type_5	8..220	CDD:239722	53/199 (27%)