DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2R2 and pup1

DIOPT Version :9

Sequence 1:	NP_649515.3	Gene:	Prosbeta2R2 / 40621	FlyBaseID:	FBgn0037296	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_594544.1	Gene:	pup1 / 2541805	PomBaseID:	SPAC23D3.07	Length:	267	Species:	Schizosaccharomyces pombe

Alignment Length:	206	Identity:	82/206 - (39%)
Similarity:	128/206 - (62%)	Gaps:	1/206 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GFTFDNCLRNKQLKENGLEEPNSFTTGTTVVGIVFDGGVIIGAESRATSGGIVFSKTCRKIIELQ 87
            ||.|:...||..|:|.|...|.:.:||||:||::....:::||::|||:|.|:..|.|:|:..:.
pombe     9 GFDFEYYQRNLLLQEKGFPTPKATSTGTTIVGVIAKDCIVLGADTRATAGPIIADKNCKKLHLIS 73

  Fly    88 ANIFAAGAGTARDTKALVELTRAQLELHRMNTGFRKVPVCCANQMIRQLLFRFNGNIDADMIIGG 152
            .||:.||||||.||:.:..:..:.:|||.:.|. ||..|..|..|::|.|||:.|:|.|.:::||
pombe    74 PNIWCAGAGTAADTEFVTSMISSNIELHSLYTN-RKPRVVTALTMLKQHLFRYQGHIGAYLVLGG 137

  Fly   153 ADNTGAHLFCTRSDGSTDTAPFTSIGSGYQVSMSILESRWSEDLSEESACALACDAVAAGMKNDL 217
            .|..|.|||...:.||:|..|:.::|||...::|:||:::..||....|..|..:|:.||:.|||
pombe   138 YDCKGPHLFTIAAHGSSDKLPYVALGSGSLAAISVLETKYQPDLERHEAMELVKEAIEAGIFNDL 202

  Fly   218 CSGGKVSLCVV 228
            .||....|.|:
pombe   203 GSGSNCDLVVI 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R2	NP_649515.3	PRE1	9..228	CDD:223711	81/204 (40%)
Prosbeta2R2	NP_649515.3	proteasome_beta_type_7	50..239	CDD:239732	71/179 (40%)
pup1	NP_594544.1	PRE1	10..237	CDD:223711	81/205 (40%)
		proteasome_beta_type_7	36..224	CDD:239732	71/179 (40%)
		Pr_beta_C	228..>253	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53608
OrthoFinder	1	1.000	-	-		FOG0001188
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880