DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Prosbeta2R2 and PSMB11

DIOPT Version :9

Sequence 1:NP_649515.3 Gene:Prosbeta2R2 / 40621 FlyBaseID:FBgn0037296 Length:322 Species:Drosophila melanogaster
Sequence 2:NP_001093250.1 Gene:PSMB11 / 122706 HGNCID:31963 Length:300 Species:Homo sapiens


Alignment Length:287 Identity:73/287 - (25%)
Similarity:116/287 - (40%) Gaps:58/287 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 EPNSF--------TTGTTVVGIVFDGGVIIGAESRATSGGIVFSKTCRKIIELQANIFAAGAGTA 98
            :|.:|        ..|||.:...|..|||..|::|::.|..|......|:|.:..::....:||:
Human    34 DPQTFLQIHGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTS 98

  Fly    99 RDTKALVELTRAQLELHRMNTGFRKVP-VCCANQMIRQLLFRFNGNIDADMIIG----GADNTGA 158
            .|......:.:.:|.|..:..|  ::| |..|.:::..::.::.|   .|:.:.    |.|.:|.
Human    99 ADCATWYRVLQRELRLRELREG--QLPSVASAAKLLSAMMSQYRG---LDLCVATALCGWDRSGP 158

  Fly   159 HLFCTRSDGSTDTAPFTSIGSGYQVSMSILESRWSEDLSEESACALACDAVAAGMKNDLCSGGKV 223
            .||...|||:.......|:|||...:..:|:..:..|:|.:.|.|||..|||.....|..|||.|
Human   159 ELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSV 223

  Fly   224 SLC---------VVRCDFSVQWPEQLPRQVPPTRTYRLSPKPGRTTILSTLVHPVLSWRGALALP 279
            .|.         |.|.|..|.:.|                       |..|:.|......:.|.|
Human   224 DLFHVRESGWEHVSRSDACVLYVE-----------------------LQKLLEPEPEEDASHAHP 265

  Fly   280 EPGGS------QEPGRGPG--TSGAAR 298
            ||..:      :|...|||  |.|.:|
Human   266 EPATAHRAAEDRELSVGPGEVTPGDSR 292

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosbeta2R2NP_649515.3 PRE1 9..228 CDD:223711 54/207 (26%)
proteasome_beta_type_7 50..239 CDD:239732 55/202 (27%)
PSMB11NP_001093250.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..23
proteasome_beta_type_5 50..237 CDD:239730 51/191 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 255..300 11/38 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.