Protein Alignment cno and YPR089W

DIOPT Version :10

• Sequence 1: NP_524232.2
• Gene: cno / 40620
• FlyBaseID: FBgn0259212
• Length: 2051
• Species: Drosophila melanogaster
• Sequence 2: NP_015414.2
• Gene: YPR089W / 856204
• SGDID: S000006293
• Length: 888
• Species: Saccharomyces cerevisiae
• Alignment Length: 533
• Identity: 102/533 - (19%)
• Similarity: 177/533 - (33%)
• Gaps: 183/533 - (34%)

  Fly  1600 RQW----REQQISELSQIVSRSPMQEEQLKTLILERDFERRAQELQEQEEQDQEQQ--------- 1651
            |.|    :.:|...|.:..:|..::|:|.|.|      .|::|..:..||::.:|.
Yeast   438 RDWNFFKKRKQAKLLLKEKNRKQLKEQQKKEL------HRKSQGQENHEEEEGQQDGNDSDDRAS 496

  Fly  1652 ------------YDKENVQELFRLAGGGQVSAIQTPITSYRQTEIKLAEMPDSNSLVDSVPPQPP 1704
                        ||||.::.|:..:...|:          :.:.:|:.::..:.|.|.::....|
Yeast   497 TNDDNNSSVSLFYDKEILRHLYPPSFEEQM----------KPSPLKIVQIFGALSYVLNLHQTHP 551

  Fly  1705 APTAQPLSSN-----TQQPKSILKHNRYSEGGVGPSGAPSSPSKSQKSASFADERHLHTEHPISN 1764
            ....|.||.:     |.....|||..:                          :|.|...|.|.
Yeast   552 IFQQQCLSISVNWFATTLFNKILKDKK--------------------------KRSLSRAHAIQ- 589

  Fly  1765 LAKELNQLTMLDKDNNNETLDAVVPPPPPPERNSSYLI---MSQQKLRGSTGNATSSMGLLKTAT 1826
              ..||..|:.....||   |..||.|        .||   |.|:          ..|.|::.
Yeast   590 --IRLNLSTLESWIQNN---DFCVPKP--------MLIDDFMWQR----------FPMTLIRD-- 629

  Fly  1827 SNQAAAAVEIKKASLLNTQT-----NNNNNLSGSLNNNTMHGSPLSAME-------------LNA 1873
                ...:::....|.|..|     .||.:|....:|:..:..|...:.             |..
Yeast   630 ----VGEIDLSDPILRNVATYKPIDENNKDLIYDTSNSLFYYQPFHKIAQIHLEPVFQLLQWLQV 690

  Fly  1874 AYVSATGTGIIGGLGTPPPPPPL-MQRDNKRVSFHDEENNFVSGNSQQQQLQQQYIMDNYGMEHQ 1937
            |....:...:|..:...|...|: :.:..::.::...||.|   ||:.::.....|.|: .|...
Yeast   691 ATTLDSEESLISTMNLLPRITPVQLLKSMEKYNYELNENKF---NSKLKKFLNNKIKDS-KMSKA 751

  Fly  1938 DLDTIREDTSYLQ-HNLDASMLPSMPATPDAALWNTSVQS------TPGVIGAQEVY-------- 1987
            |        :||| |.:...:||::|...|  |::....|      .||.| ..:||
Yeast   752 D--------AYLQEHEIPYLVLPTIPEMTD--LYSKGPDSHSFQPFLPGSI-QDDVYEIHDVNFK 805

  Fly  1988 ---RDPRTRRL---------AEKQQQQQQQRAGDAV-------PEKLSFKEKMKMFALESGEDKT 2033
               .:|:..|.         .|.:.|.:.:..|:::       ||..:|         ..|.|..
Yeast   806 QRQNEPQISRTNSGTSDFTGDEDKAQYETEGVGESIDINETVEPESNAF---------NVGNDDY 861

  Fly  2034 PKD-KLKISRAQR 2045
            .|: .:..|.|||
Yeast   862 FKELNIPSSTAQR 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cno	NP_524232.2	RA1_Afadin	20..130	CDD:340480
		RA2_Afadin	257..347	CDD:340479
		FHA	376..471	CDD:469597
		Myo5p-like_CBD_afadin	631..941	CDD:271255
		PDZ_AFDN-like	1008..1096	CDD:467251
YPR089W	NP_015414.2	Ank_2	67..152	CDD:463710
		Myo5p-like_CBD_DIL_ANK	275..776	CDD:271257	81/423 (19%)