DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr16 and Igsf9

DIOPT Version :9

Sequence 1:	NP_001287169.1	Gene:	dpr16 / 40619	FlyBaseID:	FBgn0037295	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001139272.1	Gene:	Igsf9 / 93842	MGIID:	2135283	Length:	1179	Species:	Mus musculus

Alignment Length:	265	Identity:	62/265 - (23%)
Similarity:	94/265 - (35%)	Gaps:	99/265 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 QAGQHAYLPCKLNQHSGKP----LSWVRLRDEHIIAVDHTTFINDARFASLLQSTTLTTLVSGGA 271
            :||:.|.|.|.|...:|.|    :.|:                   ||..|     |...:..|.
Mouse    32 RAGESAVLGCDLLPPAGHPPLHVIEWL-------------------RFGFL-----LPIFIQFGL 72

  Fly   272 LSTTATPVAALGNSFAHAVPGGQERGNSSSLSWTLQIKYVNLEDAGWYECQLATEPKMSAK---- 332
            .|....|...           |:.|..:.:   :|||:.:.:||.|||||::....:.|.:
Mouse    73 YSPRIDPDYV-----------GRVRLQTGA---SLQIEGLRVEDQGWYECRVLFLDQHSPEQDFA 123

  Fly   333 ----VQLFVITP-----RTELIGDRQRFVKAGSRVELHCIVRGTLEAPKYIFW-YRGDQ------ 381
                |.|.|.:|     ...|:.:    ||....|.|.|:.||:.:  .|:.| :||..
Mouse   124 NGSWVHLTVNSPPQFQETPPLVLE----VKELEAVTLRCVARGSPQ--PYVTWKFRGQDLGKGQG 182

  Fly   382 QVTAENEASGAQSGWYTQIDRNIFGSTEHNRNTIGSLVIPLVRKIHSGNYTCE---PENSAAASM 443
            ||..:|                            |:|.|..|.:..:|:|||:   .|.|...:.
Mouse   183 QVQVQN----------------------------GTLWIRRVERGSAGDYTCQASSSEGSITHAT 219

  Fly   444 QLHVL 448
            ||.||
Mouse   220 QLLVL 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr16	NP_001287169.1	IG_like	205..337	CDD:214653	31/137 (23%)
		Ig	<298..338	CDD:299845	13/47 (28%)
		IG_like	352..447	CDD:214653	26/104 (25%)
		Ig	358..439	CDD:143165	21/90 (23%)
Igsf9	NP_001139272.1	IG_like	28..110	CDD:214653	28/115 (24%)
		Ig	136..223	CDD:386229	27/120 (23%)
		Ig_3	227..305	CDD:372822
		Ig	341..404	CDD:386229
		Ig	436..500	CDD:319273
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	767..807
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..842
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..974
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900