DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr16 and cadm2

DIOPT Version :9

Sequence 1:NP_001287169.1 Gene:dpr16 / 40619 FlyBaseID:FBgn0037295 Length:488 Species:Drosophila melanogaster
Sequence 2:XP_031751706.1 Gene:cadm2 / 448238 XenbaseID:XB-GENE-998536 Length:441 Species:Xenopus tropicalis


Alignment Length:329 Identity:66/329 - (20%)
Similarity:95/329 - (28%) Gaps:135/329 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly   207 NATVQAGQHAYLPCKLNQHSGKPLSWVRLRDEHIIAVDHTTFINDARFASLLQSTTLTTLVSGGA 271
            |.||..|....|.|:::|:....|.|..       ....|.:.:|.:                  
 Frog    39 NVTVVEGGTINLTCRVDQNDNTSLQWSN-------PAQQTLYFDDKK------------------ 78

  Fly   272 LSTTATPVAALGNSFAHAVPGGQERGNSSSL---SW---TLQIKYVNLEDAGWYECQLATEPKMS 330
                     ||             |.|...|   ||   ::.|..|:|.|.|.|.|.|.|.|..:
 Frog    79 ---------AL-------------RDNRIELVRASWHELSISISDVSLSDEGQYTCSLFTMPVKT 121

  Fly   331 AKVQLFVI-TPRTELIGDRQRFVKAGSRVELHCIVRGTLEAPKYIFWYRGDQQVT-----AENEA 389
            :|..|.|: .|....|......|..|..::|.|...|:..|.. |.|::.||::|     .:.::
 Frog   122 SKAYLMVLGVPENPHISGFTSPVMEGDTIQLTCKSSGSKPAAD-IRWFKNDQEITDVQKIQQQDS 185

  Fly   390 SG----AQSGWYTQIDR-----------------------------------NIFGST------- 408
            :|    ..|....|.||                                   .|..||       
 Frog   186 NGKTFTVTSSLVFQGDRKDDGAVIRCRVDHESLTSTPQIAKQVLEIHYTPTVRILPSTPLPQEGQ 250

  Fly   409 ---------------------------EHNRNTIG--SLVIPLVRKIHSGNYTCEPENSAAASMQ 444
                                       :..|.|:.  .|.|..:.|..:|.|.||..||...|..
 Frog   251 PLILICESKGKPLPEPVLWTKDGGELPDPERMTVNGRELTISFLNKTDNGTYRCEATNSIGQSSA 315

  Fly   445 LHVL 448
            .:||
 Frog   316 EYVL 319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr16NP_001287169.1 IG_like 205..337 CDD:214653 30/135 (22%)
Ig <298..338 CDD:299845 16/45 (36%)
IG_like 352..447 CDD:214653 31/174 (18%)
Ig 358..439 CDD:143165 27/160 (17%)
cadm2XP_031751706.1 IgV_1_Necl-3 34..129 CDD:409498 30/136 (22%)
Ig strand B 48..52 CDD:409498 1/3 (33%)
Ig strand C 61..65 CDD:409498 1/3 (33%)
Ig strand E 95..99 CDD:409498 0/3 (0%)
Ig strand F 109..114 CDD:409498 2/4 (50%)
Ig strand G 121..124 CDD:409498 0/2 (0%)
IgI_2_Necl-3 128..231 CDD:409467 19/103 (18%)
Ig strand B 150..154 CDD:409467 1/3 (33%)
Ig strand C 164..168 CDD:409467 1/4 (25%)
Ig strand E 194..198 CDD:409467 1/3 (33%)
Ig strand F 208..213 CDD:409467 0/4 (0%)
Ig strand G 224..227 CDD:409467 0/2 (0%)
IGc2 248..311 CDD:197706 11/62 (18%)
Ig strand B 250..259 CDD:409353 0/8 (0%)
Ig strand C 265..271 CDD:409353 0/5 (0%)
Ig strand C' 274..277 CDD:409353 0/2 (0%)
Ig strand D 280..285 CDD:409353 2/4 (50%)
Ig strand E 286..293 CDD:409353 2/6 (33%)
Ig strand F 300..308 CDD:409353 4/7 (57%)
Ig strand G 311..321 CDD:409353 3/9 (33%)
4.1m 394..412 CDD:128590
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 82 1.000 Inparanoid score I5030
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.960

Return to query results.
Submit another query.