DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr16 and Cadm3

DIOPT Version :9

Sequence 1:	NP_001287169.1	Gene:	dpr16 / 40619	FlyBaseID:	FBgn0037295	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_006250385.1	Gene:	Cadm3 / 360882	RGDID:	1307035	Length:	430	Species:	Rattus norvegicus

Alignment Length:	443	Identity:	93/443 - (20%)
Similarity:	141/443 - (31%)	Gaps:	158/443 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 PADLPHMLRNASSGAAPPADIGPSGSPMPSKPNEQSRLHAYDSEQKAQQLRREKEL---AKEREL 195
            |:.||.:|..|.|.|...|::...|               |..||       :.||   |...|.
  Rat     4 PSALPLLLLLACSWAPGGANLSQDG---------------YWQEQ-------DLELGTPAPLEEA 46

  Fly   196 LPRRQLSLPPLNA-----------TVQAGQHAYLPCKLNQHSGKPLSWVR-------------LR 236
            |.....|.|.|.|           ||.||....|.|::..|....|.|..             ||
  Rat    47 LSSTVWSNPDLLASQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALR 111

  Fly   237 DEHIIAVDHT----------------------TFINDARFASLL-------QSTTLTTLVSGGAL 272
            |..|..|..|                      .|....|.|..|       |...:|...|....
  Rat   112 DNRIQLVSSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLRE 176

  Fly   273 STTAT---------PVAAL----GNSFAHAVPGGQER------GNSSSLSWTLQIKYVNLEDAGW 318
            ..|||         |.|.|    |:...|   |.|.|      |.:.::|.::..:....:|...
  Rat   177 KETATLNCQSSGSKPAAQLAWRKGDQELH---GDQTRIQEDPNGKTFTVSSSVSFQVTRDDDGAN 238

  Fly   319 YECQLATE----PKMSAKVQLFVITPRTELIGDRQRFVKAGSRVELHCIVRGTLEAPKYIFWYRG 379
            ..|.:..|    ...|...::.|:...|.:|.......:.|.::.|||..||.....:|::...|
  Rat   239 VVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPEPAHPREGQKLLLHCEGRGNPVPQQYVWVKEG 303

  Fly   380 DQ---QVTAENEASGAQSGWYTQIDRNIFGSTEHNRNTIGSLVIPLVRKIHSGNYTCEPENSAAA 441
            .:   ::|.|:                             :|:.|.:.|..||.|.|    :|.:
  Rat   304 SEPPLKMTQES-----------------------------ALIFPFLNKSDSGTYGC----TATS 335

  Fly   442 SMQLHVLSGEYSA---------SAIKSTAARPHRLGHGYTSLHQWLIFLLVAL 485
            :|      |.|:|         |.:.|:::..|.:..|..:   :::|||:.|
  Rat   336 NM------GSYTAYFTLNVNDPSPVPSSSSTYHAIIGGIVA---FIVFLLLIL 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr16	NP_001287169.1	IG_like	205..337	CDD:214653	41/207 (20%)
		Ig	<298..338	CDD:299845	5/43 (12%)
		IG_like	352..447	CDD:214653	19/97 (20%)
		Ig	358..439	CDD:143165	16/83 (19%)
Cadm3	XP_006250385.1	Ig1_Necl-1	64..158	CDD:143290	19/93 (20%)
		IG_like	68..>142	CDD:214653	15/73 (21%)
		IG_like	175..244	CDD:214653	15/71 (21%)
		Ig	179..261	CDD:299845	17/84 (20%)
		Ig_2	269..348	CDD:290606	23/117 (20%)
		IG_like	271..348	CDD:214653	22/115 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I5126
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960