DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr16 and Negr1

DIOPT Version :9

Sequence 1:NP_001287169.1 Gene:dpr16 / 40619 FlyBaseID:FBgn0037295 Length:488 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:338 Identity:68/338 - (20%)
Similarity:112/338 - (33%) Gaps:119/338 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   207 NATVQAGQHAYLPCKLNQHSGKPLSWVRLRDEHIIAVDHTTFINDARFASLLQSTTLTTLVSGGA 271
            |..|:.|..|.|.|.|...:.|. :|  |....||......:..|.|       .:::||     
Mouse    41 NMLVRKGDTAVLRCYLEDGASKG-AW--LNRSSIIFAGGDKWSVDPR-------VSISTL----- 90

  Fly   272 LSTTATPVAALGNSFAHAVPGGQERGNSSSLSWTLQIKYVNLEDAGWYECQLATE--PKMSAKVQ 334
                                        :...::|||:.|::.|.|.|.|.:.|:  |: :.:|.
Mouse    91 ----------------------------NKRDYSLQIQNVDVTDDGPYTCSVQTQHTPR-TMQVH 126

  Fly   335 LFVITPRTELIGDRQRFVKAGSRVELHCIVRG----------------TLEAPKYIFWY------ 377
            |.|..|...........:..|:.|.|.|:..|                ..|..:|:..|      
Mouse   127 LTV
QVPPKIYDISNDMTINEGTNVTLTCLATGKPEPVISWRHISPSAKPFENGQYLDIYGITRDQ 191

  Fly   378 RGDQQVTAENEAS--------------------------GAQSG---------------WYTQID 401
            .|:.:.:|||:.|                          ..:||               || :.:
Mouse   192 AGEYECSAENDVSFPDVKKVRVIVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWY-KGE 255

  Fly   402 RNIFGSTE----HNRNTIGSLVIPLVRKIHSGNYTCEPEN---SAAASMQLHVLSGEYSASAIKS 459
            :.:|...:    .|.:|...|.:..|.:.|.|||||...|   :..||:.|:.:....::|.:.|
Mouse   256 KRLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNQIIEPTTSSPVTS 320

  Fly   460 TAARPHRLGHGYT 472
            .|  |....:|.|
Mouse   321 PA--PSTAQYGIT 331

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr16NP_001287169.1 IG_like 205..337 CDD:214653 28/131 (21%)
Ig <298..338 CDD:299845 12/41 (29%)
IG_like 352..447 CDD:214653 32/164 (20%)
Ig 358..439 CDD:143165 28/150 (19%)
Negr1XP_036019026.1 FR1 38..55 CDD:409353 5/13 (38%)
Ig strand A' 40..46 CDD:409353 2/4 (50%)
IG_like 41..129 CDD:214653 28/131 (21%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 1/3 (33%)
FR2 61..68 CDD:409353 3/9 (33%)
Ig strand C 61..67 CDD:409353 2/8 (25%)
CDR2 69..79 CDD:409353 2/9 (22%)
Ig strand C' 71..74 CDD:409353 2/2 (100%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 12/74 (16%)
Ig strand D 84..91 CDD:409353 3/46 (7%)
Ig strand E 94..100 CDD:409353 2/5 (40%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 3/9 (33%)
FR4 122..129 CDD:409353 2/6 (33%)
Ig strand A' 139..144 CDD:409353 0/4 (0%)
IGc2 146..204 CDD:197706 12/57 (21%)
Ig strand B 150..157 CDD:409353 3/6 (50%)
Ig strand C 163..168 CDD:409353 0/4 (0%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 1/5 (20%)
Ig strand F 193..200 CDD:409353 1/6 (17%)
Ig_3 219..295 CDD:404760 15/76 (20%)
putative Ig strand A 219..225 CDD:409353 0/5 (0%)
Ig strand B 235..239 CDD:409353 1/3 (33%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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