DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr16 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_001287169.1	Gene:	dpr16 / 40619	FlyBaseID:	FBgn0037295	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001363879.1	Gene:	Igsf9b / 315510	RGDID:	1564717	Length:	1441	Species:	Rattus norvegicus

Alignment Length:	422	Identity:	93/422 - (22%)
Similarity:	123/422 - (29%)	Gaps:	154/422 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 VLMLGDDQQQQEYDTTVVDSW----SDRPDTATLTKGFSIPSYLPPFPEFIPADLPHMLRNASSG 147
            ||||     .|:|||....||    .:.|.|.|.|.           |::|         .|..|
  Rat   115 VLML-----DQQYDTFHNGSWVHLTINAPPTFTETP-----------PQYI---------EAKEG 154

  Fly   148 AAPPADIGPSGSPMP--------SKPNEQSRLHAYDSEQKAQQLRREKELAKERELLPRRQLSL- 203
            .:........|:|.|        :..:...:....|.......:.||     :|.....|..|:
  Rat   155 GSITMTCTAFGNPKPIVTWLKEGTLLSASGKYQVSDGSLTVTSVSRE-----DRGAYTCRAYSIQ 214

  Fly   204 -------------------PPLNATVQAGQHAYLPCKLNQHSGK-PLSWVRLRDEHIIAVDHTTF 248
                               ||.|.||...|.|.|.|:...:.|. ..:|. .:||::.      |
  Rat   215 GEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWY-WQDENVY------F 272

  Fly   249 INDARFASLLQSTTLTTLVSGGALSTTATPVAALGNSFAHAVPGGQERGNSSSLSWTLQIKYVNL 313
            .||.:.       .:..|:.|                                   ||.|..|..
  Rat   273 QNDLKL-------RVRILIDG-----------------------------------TLIIFRVKP 295

  Fly   314 EDAGWYEC----QLATEPKMSAKVQLFVITPRTELIGDRQRFVKAGSRVELHCIVRGTLEAPKYI 374
            ||||.|.|    .|...|  ||...|.|..|...|......:|..|....:.|.|  ..|.|..:
  Rat   296 EDAGKYTCVPSNSLGRSP--SASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPV--DAEPPATV 356

  Fly   375 F-WYRGDQQVTAENEASGAQSGWYTQIDRNIFGSTEHNRNTIGSLVIPLVRKIHSGNYTCEPEN- 437
            . |.:..:.:..|...     ||....|              ||:.|....:...|.|||.|.|
  Rat   357 VKWNKDGRPLQVEKNL-----GWTLMED--------------GSIRIEEATEEALGTYTCVPYNT 402

  Fly   438 ------SAAASMQLH------VLSG-EYSASA 456
                  ||.|.:.|.      ||.| ||...|
  Rat   403 LGTMGQSAPARLVLKDPPYFTVLPGWEYRQEA 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr16	NP_001287169.1	IG_like	205..337	CDD:214653	32/136 (24%)
		Ig	<298..338	CDD:299845	15/43 (35%)
		IG_like	352..447	CDD:214653	24/108 (22%)
		Ig	358..439	CDD:143165	18/88 (20%)
Igsf9b	NP_001363879.1	PHA03247	<898..1246	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	918..1044
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1111..1332
		Ig	41..115	CDD:319273	93/422 (22%)
		I-set	139..225	CDD:369462	16/110 (15%)
		Ig	229..321	CDD:386229	33/142 (23%)
		Ig	<353..414	CDD:386229	18/79 (23%)
		Ig	438..502	CDD:319273
		FN3	510..605	CDD:238020
		FN3	621..703	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	762..821
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900