DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr16 and Lrit1

DIOPT Version :9

Sequence 1:NP_001287169.1 Gene:dpr16 / 40619 FlyBaseID:FBgn0037295 Length:488 Species:Drosophila melanogaster
Sequence 2:NP_647547.2 Gene:Lrit1 / 246214 RGDID:628607 Length:623 Species:Rattus norvegicus


Alignment Length:379 Identity:90/379 - (23%)
Similarity:126/379 - (33%) Gaps:119/379 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   139 HMLRNASSG----------AAPPADIGPSGSPMPSK-------PNEQ----SRLH----AYD--S 176
            |:|.:.|..          ..|||.|.|....:..:       |.|.    |||.    .|:  |
  Rat    32 HILSDGSKARTVVCSDPDLTLPPASIPPDTCKLRLERTAIRRVPGETFRPLSRLEQLWLPYNALS 96

  Fly   177 EQKAQQLRREKELAKEREL-LPRRQLSLPPLNATVQAGQHAYLPCKLNQHSGKPLSWVRLRDEHI 240
            |.....||..:.|   ||| ||...|...|..|.....|...|..:.|:.|..|       .|.:
  Rat    97 ELSTLMLRGLRRL---RELRLPGNHLVTFPWAALKDTPQLQLLDLQANRLSTLP-------PEAV 151

  Fly   241 IAVDHTTFINDARFASLLQ-----STTLTTLVSGGALSTTATPVAALGNSFAHAVPGGQERGNSS 300
            ..:::.||: |.....|::     ..|...|.:|..||:..|          ..|.|.|:.    
  Rat   152 HFLENLTFL-DLSNNQLMRLPEELLDTWAHLKTGPYLSSRRT----------RLVLGLQDN---- 201

  Fly   301 SLSWTLQIK---YVNLEDAGW------YECQL-ATEPKMSAKVQLFVITPR-----------TEL 344
              .|....:   .|:|.| ||      .|.:| ...|:..|.|....:..|           |.:
  Rat   202 --PWVCDCRLYDLVHLLD-GWASNLIFIEARLRCGSPRSLAGVAFSQLELRKCQSPELRPGVTSI 263

  Fly   345 IGDRQRFVKAGSRVELHCIVRGTLEAPKYIFWYRGDQQV---TAENEASGAQSGWYTQIDRNIFG 406
            |.      ..||.|.|.|...| :..|: :.|.|.:.:.   |...|.|...|.| |.:|     
  Rat   264 IS------PLGSTVLLRCGATG-IPGPE-MSWRRANGRPLNGTVHQEVSSDGSSW-TLLD----- 314

  Fly   407 STEHNRNTIGSLVIPLVRKIHSGNYTCEPENSAAASMQLHVL-------SGEYS 453
                         :|:|....||:|.|:.:|...||..|..|       |.||:
  Rat   315 -------------LPVVSLFDSGDYICQAKNFLGASETLISLIVTEPQTSTEYT 355

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr16NP_001287169.1 IG_like 205..337 CDD:214653 32/146 (22%)
Ig <298..338 CDD:299845 11/49 (22%)
IG_like 352..447 CDD:214653 26/97 (27%)
Ig 358..439 CDD:143165 21/83 (25%)
Lrit1NP_647547.2 LRRNT 23..61 CDD:214470 8/28 (29%)
LRR 1 60..81 2/20 (10%)
LRR_8 63..143 CDD:290566 22/82 (27%)
leucine-rich repeat 64..84 CDD:275378 2/19 (11%)
LRR 2 84..105 6/20 (30%)
leucine-rich repeat 85..132 CDD:275378 15/49 (31%)
LRR 3 108..128 9/22 (41%)
LRR_8 131..>176 CDD:290566 10/52 (19%)
LRR_4 131..172 CDD:289563 10/48 (21%)
LRR 4 132..153 6/27 (22%)
leucine-rich repeat 133..156 CDD:275378 5/29 (17%)
LRR 5 156..177 4/21 (19%)
leucine-rich repeat 157..180 CDD:275378 5/23 (22%)
leucine-rich repeat 181..205 CDD:275378 9/39 (23%)
TPKR_C2 201..>240 CDD:301599 9/45 (20%)
Ig 257..345 CDD:299845 29/114 (25%)
IG_like 267..345 CDD:214653 27/98 (28%)
FN3 431..501 CDD:214495
LRR 6 525..548
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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