DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr16 and Lrit3

DIOPT Version :9

Sequence 1:NP_001287169.1 Gene:dpr16 / 40619 FlyBaseID:FBgn0037295 Length:488 Species:Drosophila melanogaster
Sequence 2:NP_001274153.1 Gene:Lrit3 / 242235 MGIID:2685267 Length:681 Species:Mus musculus


Alignment Length:325 Identity:65/325 - (20%)
Similarity:110/325 - (33%) Gaps:117/325 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   221 KLNQHSGKPLSWVRLRD-EHIIAVDHTTFINDARFASL---------------LQSTTLTTLVSG 269
            :|:.:|.....||.|.| .|:..:|    :::.|.||:               |.|..||||   
Mouse   111 RLDGNSLTAFPWVSLLDMPHLRTLD----LHNNRIASVPNEAVRYLRNLTCLDLSSNRLTTL--- 168

  Fly   270 GALSTTATPVAALGNSFAH--AVPGGQERGNSSSLSWTLQIKYVNLEDAGWY-ECQLATEPKMS- 330
                    |...| :|::|  ..|       |.|..:..:...:.|:|..|: :|.::...::| 
Mouse   169 --------PPDFL-DSWSHLAVTP-------SRSPDFPPRRIILGLQDNPWFCDCHISKVIELSK 217

  Fly   331 ---------------AKVQLF--VITPRTELIGDRQRFVK-------------AGSRVELHCIVR 365
                           ::.:.|  ::..|.||    ::.:|             .||.|.|.|..:
Mouse   218 VTDHAVVLLDPLMVCSEPERFQGILFQRVEL----EKCLKPSVMMSATKITSALGSNVLLRCDAK 278

  Fly   366 GTLEAPKYIFWYRGDQQV---TAENEASGAQSGWYTQIDRNIFGSTEHNRNTIGSLVIPLVRKIH 427
            |  .....:.|.|.|...   |...|:.|....|                     .:|.|....|
Mouse   279 G--HPTPQLTWTRSDGSTVNYTVIQESPGEGIRW---------------------SIISLTSISH 320

  Fly   428 --SGNYTCEPENSAAAS---MQLHVLSGEYSA----SAIKSTAARPHR-----LGHGYTSLHQWL 478
              :|:|.|:.:|.|..|   :.:.|:.|..:.    |:.:|....|.:     ||........||
Mouse   321 KDAGDYRCKAKNLAGISEAVVTVTVVGGVTTTLSPDSSERSPGEPPEQHPQPGLGGSTPPSKSWL 385

  Fly   479  478
            Mouse   386  385

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr16NP_001287169.1 IG_like 205..337 CDD:214653 30/152 (20%)
Ig <298..338 CDD:299845 8/58 (14%)
IG_like 352..447 CDD:214653 23/115 (20%)
Ig 358..439 CDD:143165 18/85 (21%)
Lrit3NP_001274153.1 LRR 1. /evidence=ECO:0000255 56..79
LRR_8 61..117 CDD:290566 1/5 (20%)
LRR 2. /evidence=ECO:0000255 80..103
leucine-rich repeat 83..106 CDD:275378
LRR 3. /evidence=ECO:0000255 104..128 5/16 (31%)
LRR_8 105..165 CDD:290566 13/57 (23%)
LRR_4 106..146 CDD:289563 11/38 (29%)
leucine-rich repeat 107..130 CDD:275378 6/18 (33%)
LRR_4 129..170 CDD:289563 11/55 (20%)
LRR 4. /evidence=ECO:0000255 129..151 5/25 (20%)
leucine-rich repeat 131..154 CDD:275378 4/26 (15%)
LRR 5. /evidence=ECO:0000255 152..175 8/34 (24%)
leucine-rich repeat 155..168 CDD:275378 4/12 (33%)
Ig 254..335 CDD:299845 20/103 (19%)
IG_like 263..339 CDD:214653 22/98 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 350..391 7/36 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 425..464
FN3 489..563 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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