DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr16 and Iglon5

DIOPT Version :9

Sequence 1:NP_001287169.1 Gene:dpr16 / 40619 FlyBaseID:FBgn0037295 Length:488 Species:Drosophila melanogaster
Sequence 2:NP_001157990.1 Gene:Iglon5 / 210094 MGIID:2686277 Length:336 Species:Mus musculus


Alignment Length:322 Identity:74/322 - (22%)
Similarity:118/322 - (36%) Gaps:93/322 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   200 QLSLPPLNATVQAGQHAYLPCKLNQHSGKPLSWVRLRDEHIIAVDHTTFINDARFASLLQS---- 260
            :.|.|..|.||..|.:|.|.|.:::|..: ::|  |...:|:...:..:.:|.|...|:.:    
Mouse    34 EFSSPADNYTVCEGDNATLSCFIDEHVTR-VAW--LNRSNILYAGNDRWTSDPRVRLLINTPEEF 95

  Fly   261 TTLTTLVSGG-------ALSTTATPVAALGNSFAHAVPGG----------QERGN---------- 298
            :.|.|.|..|       :..|...|.........| ||..          .|.||          
Mouse    96 SILITQVGLGDEGLYTCSFQTRHQPYTTQVYLIVH-VPARIVNISSPVAVNEGGNVNLLCLAVGR 159

  Fly   299 -SSSLSW------------TLQIKYVNLEDAGWYEC----QLATEPKMSAKVQLFVITPR--TEL 344
             ..:::|            .|:|..:....||.|||    .:.:.|. |.:|.:.|..|.  |::
Mouse   160 PEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPD-SRRVLVTVNYPPTITDV 223

  Fly   345 IGDRQRFVKAGSRVELHCIVRGTLEA----PKYIFWYRGDQQVTAENEASGAQSGWYTQIDRNIF 405
            ...|   ...|....|.|      ||    |....||:.|:.:     :||:..|...|.:|   
Mouse   224 TSAR---TALGRAALLRC------EAMAVPPADFQWYKDDRLL-----SSGSAEGLKVQTER--- 271

  Fly   406 GSTEHNRNTIGSLVIPLVRKIHSGNYTCEPEN---SAAASMQLHVLSGEYSASAIKSTAARP 464
                    |...|:...|...|.|||||...|   :::|||:|      ....:::::|.||
Mouse   272 --------TRSMLLFANVSARHYGNYTCRAANRLGASSASMRL------LRPGSLENSAPRP 319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr16NP_001287169.1 IG_like 205..337 CDD:214653 37/179 (21%)
Ig <298..338 CDD:299845 12/66 (18%)
IG_like 352..447 CDD:214653 28/101 (28%)
Ig 358..439 CDD:143165 23/87 (26%)
Iglon5NP_001157990.1 Ig 41..129 CDD:416386 20/90 (22%)
Ig strand A' 41..46 CDD:409353 3/4 (75%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 0/3 (0%)
FR2 61..68 CDD:409353 2/9 (22%)
Ig strand C 61..67 CDD:409353 1/8 (13%)
CDR2 69..79 CDD:409353 1/9 (11%)
Ig strand C' 71..74 CDD:409353 1/2 (50%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 7/34 (21%)
Ig strand D 84..91 CDD:409353 2/6 (33%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 0/7 (0%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 1/8 (13%)
FR4 122..129 CDD:409353 0/6 (0%)
Ig strand A 132..137 CDD:409353 1/4 (25%)
Ig_3 134..199 CDD:404760 11/64 (17%)
Ig strand A' 140..145 CDD:409353 0/4 (0%)
Ig strand B 148..157 CDD:409353 2/8 (25%)
Ig strand C 163..167 CDD:409353 0/3 (0%)
Ig strand D 174..177 CDD:409353 0/2 (0%)
Ig strand E 178..183 CDD:409353 1/4 (25%)
Ig strand F 191..199 CDD:409353 4/7 (57%)
Ig_3 217..295 CDD:404760 26/102 (25%)
putative Ig strand A 218..224 CDD:409353 1/5 (20%)
Ig strand B 234..238 CDD:409353 1/3 (33%)
Ig strand C 247..251 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 4/4 (100%)
Ig strand G 301..304 CDD:409353 1/2 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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