DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr16 and Ncam1

DIOPT Version :9

Sequence 1:	NP_001287169.1	Gene:	dpr16 / 40619	FlyBaseID:	FBgn0037295	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_006510118.1	Gene:	Ncam1 / 17967	MGIID:	97281	Length:	1162	Species:	Mus musculus

Alignment Length:	311	Identity:	58/311 - (18%)
Similarity:	98/311 - (31%)	Gaps:	98/311 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 LSLPP--------LNATVQAGQHAYLPCKLNQHSGKPLSWVR----LRDE------HIIAVDHT- 246
            :::||        :|||...||...|.|..:......:||.:    :.:|      ||.:.|.:
Mouse   208 VNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIENEEEDDEKHIFSDDSSE 272

  Fly   247 ---------------------------------------TFINDARFASLLQSTTLTTLVSGGAL 272
                                                   |::.:.....|.:..|||...||..:
Mouse   273 LTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPI 337

  Fly   273 ST----TATPVAALGNSFAHAVPGGQE--------RGNSSSLSWTLQIKYVNLEDAGWYECQLAT 325
            .:    |:|...:.....:...|..||        |.::...|.||  |.:...|||.|.|..:.
Mouse   338 PSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTL--KSIQYTDAGEYICTASN 400

  Fly   326 EPKMSAKVQLFVITPRTELIGDRQRFVKAGSRVELHCIVRGTLEAPKYIFWYRGDQQVTAENEAS 390
            .....::.....:....:|.|....:...|::|.:.|.|.....|.  |.|:|..|.:.:.|.::
Mouse   401 TIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSAT--ISWFRDGQLLPSSNYSN 463

  Fly   391 ----GAQSGWYTQIDRNIFGSTEHNRNTIGSLVIPLVRKIHSGNYTCEPEN 437
                ...|..|.::       |..:.|..             |||.|...|
Mouse   464 IKIYNTPSASYLEV-------TPDSENDF-------------GNYNCTAVN 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr16	NP_001287169.1	IG_like	205..337	CDD:214653	36/201 (18%)
		Ig	<298..338	CDD:299845	9/39 (23%)
		IG_like	352..447	CDD:214653	19/90 (21%)
		Ig	358..439	CDD:143165	18/84 (21%)
Ncam1	XP_006510118.1	Ig1_NCAM-1	20..115	CDD:143273
		IG	124..190	CDD:214652
		Ig3_NCAM-1_like	211..308	CDD:143207	15/96 (16%)
		Ig_NCAM-1	307..413	CDD:143277	22/107 (21%)
		Ig_3	417..494	CDD:372822	20/98 (20%)
		FN3	509..606	CDD:238020
		fn3	649..731	CDD:365830
		PHA03247	<905..1140	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810