Protein Alignment RabGGTa and M57.2

DIOPT Version :10

• Sequence 1: NP_649512.1
• Gene: RabGGTa / 40617
• FlyBaseID: FBgn0037293
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_500367.1
• Gene: M57.2 / 177113
• WormBaseID: WBGene00019778
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 167/558 - (29%)
• Similarity: 248/558 - (44%)
• Gaps: 122/558 - (21%)

  Fly     1 MHGRVKVRTTEEERERKKKEQALKVRAYRAAMGRIQKKREAGELDNEMLSLTVQILLRNPDVSML 65
            ||...||.|||||:..|:||...:.:.:.....:|..|||.||.|:|:||||..||.:|.|:...
 Worm     1 MHFVKKVPTTEEEKAAKQKEHTKRSQQFLHVRDKIVAKREKGEYDDEILSLTQAILEKNADIYTF 65

  Fly    66 WNIRRECVLEKLFRLKEEEATCETPSEEKPEKENQTGENKPSEKKAAGEDKAHSIFTCELDLTEQ 130
            |||||..:..::               |..||..|:.:.: .|:|.....|..::...||.|:.:
 Worm    66 WNIRRTTIELRM---------------EANEKVQQSADAE-EEEKTKSSQKIENLLAGELFLSYE 114

  Fly   131 CLMVNPKSYNAWHHRCWTLEQNPRADWQQEVKLCNKYLKFDERNFHTWDYRRYVTGKAMVPATQE 195
            |:..|||||:||:.|.|.|::....|:::|:.||.|.|:.|.||||.||:||.|...|.....:|
 Worm   115 CIKSNPKSYSAWYQRAWALQRQSAPDFKKELALCEKALQLDCRNFHCWDHRRIVARMAKRSEAEE 179

  Fly   196 LDFCTEKIRANFSNYSSWHHRSLLLPELYPNQQRDRP-MSEEKLQKELEMVLTAAFTDPNDSSAW 259
            |:|..:.|..||||||:||:||:.|..::.:::...| :.:|.:..||:.|..|.|.|..|.|||
 Worm   180 LEFSNKLINDNFSNYSAWHYRSIALKNIHRDEKTGAPKIDDELIASELQKVKNAFFMDAEDQSAW 244

  Fly   260 FYQRWLL--GSGAQLDRAPRIAAFRLESHGAVLALDKPYPDIKQLKTELVGGGQTIL------LE 316
            .|.||||  |||.:.        .|.|||          ..|:.:.....|...|::      ::
 Worm   245 TYTRWLLEVGSGKEF--------LRPESH----------TPIELISASFHGNNTTLVFSRAVTIQ 291

  Fly   317 FWLP-VDKRGTS-WKCQQNFD--------YQRNSAYSLR-LSDQKVDLSPLSGSE-NGAYYIAPP 369
            |.|. ||...|: |:...:..        :|..|...|| ::....||..:|.:| |...|:
 Worm   292 FLLTFVDTENTTGWRAFSSTSPNPTSSRVWQYLSDTPLRVVTSNPTDLENISWTELNEQPYV--- 353

  Fly   370 HGTTSCSKDLL------------AELQTQLQSCLDLLEFEPDSKWTLLTSALLMRAIDFSANHET 422
                  :.|.|            |.:...|:.|..|:|.||.:||.|....|::.......::|.
 Worm   354 ------NLDRLKTIYDVVEVPQPAYIGELLEDCKQLIELEPKNKWPLYMRTLVLLEYQPIKSYEE 412

  Fly   423 SLAHLAKL-EKVDFLREGYYKDLAARWTL----------------EW---------------ELA 455
            .:.:|..| |.:|..|...||.|.:|..|                :|               .||
 Worm   413 IIKNLENLSENLDPKRSELYKSLISRQNLNFSIREQFERILGPDTDWLTCRYSKLTSLEGVEYLA 477

  Fly   456 KWPQSADFP--KRFDIANAVL------------LESLP 479
            .:..||||.  :..:|...||            :||||
 Worm   478 GFVGSADFSGNRLKEIQRIVLPNLKSLTINENPIESLP 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabGGTa	NP_649512.1	BET4	21..>267	CDD:227823	91/248 (37%)
M57.2	NP_500367.1	BET4	37..>264	CDD:227823	94/250 (38%)
		LRR	322..>559	CDD:443914	48/203 (24%)
		leucine-rich repeat	501..522	CDD:275378	4/15 (27%)
		leucine-rich repeat	523..548	CDD:275378