Protein Alignment plh and MPV17L2

DIOPT Version :10

• Sequence 1: NP_649511.2
• Gene: plh / 40615
• FlyBaseID: FBgn0037292
• Length: 193
• Species: Drosophila melanogaster
• Sequence 2: NP_116072.2
• Gene: MPV17L2 / 84769
• HGNCID: 28177
• Length: 206
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 52/202 - (25%)
• Similarity: 96/202 - (47%)
• Gaps: 21/202 - (10%)

  Fly     2 FRSLVNITSKYKVL---RGMISYGTLWPCGSLI-------EQTMIEKKTFRTYDWMKCLRFSLFG 56
            :|.|..:.|..::|   |.::...|| .||:|:       :...|..:..:.:|..:.......|
Human     6 WRRLRRLLSAGQLLFQGRALLVTNTL-GCGALMAAGDGVRQSWEIRARPGQVFDPRRSASMFAVG 69

  Fly    57 FFFMGPTIYVWIRLASVMWPRTDIK---SSLCKAITEQTAYDPMAISSFLFFMTLMEGNSYAEAK 118
             ..|||.::.|......::|.:.::   :.|.|.:.:|....|:....:...:..:||.:..|:.
Human    70 -CSMGPFLHYWYLSLDRLFPASGLRGFPNVLKKVLVDQLVASPLLGVWYFLGLGCLEGQTVGESC 133

  Fly   119 REVSDKFLDAYKVGVIYWPCVQTVNFAFVPARNQVVFTSFFSMCWTTFLAYVKF---LQLHPPVD 180
            :|:.:||.:.||.....||..|.|||.|||.:.:|.:.:..::.|.|:|:|:|:   :.|.||..
Human   134 QELREKFWEFYKADWCVWPAAQFVNFLFVPPQFRVTYINGLTLGWDTYLSYLKYRSPVPLTPPGC 198

  Fly   181 VDHHALD 187
            |   |||
Human   199 V---ALD 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
plh	NP_649511.2	Mpv17_PMP22	107..168	CDD:461182	20/60 (33%)
MPV17L2	NP_116072.2	Mpv17_PMP22	122..183	CDD:461182	20/60 (33%)