Protein Alignment plh and MPV17

DIOPT Version :10

• Sequence 1: NP_649511.2
• Gene: plh / 40615
• FlyBaseID: FBgn0037292
• Length: 193
• Species: Drosophila melanogaster
• Sequence 2: NP_002428.1
• Gene: MPV17 / 4358
• HGNCID: 7224
• Length: 176
• Species: Homo sapiens
• Alignment Length: 156
• Identity: 35/156 - (22%)
• Similarity: 74/156 - (47%)
• Gaps: 8/156 - (5%)

  Fly    18 MISYGTLWPCGSLIEQTMIEKKTFRTYDWMKCLRFSLFGFFFMGPTIYVWIRLASVMWPRTDIKS 82
            :::.|:|...|.:|.|.::|::..:.:...:.|.....|..|:||.:..|.::.....|.|....
Human    20 VLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCGFVGPVVGGWYKVLDRFIPGTTKVD 84

  Fly    83 SLCKAITEQTAYDPMAISSFLFFMTLMEG----NSYAEAKREVSDKFLDAYKVGVIYWPCVQTVN 143
            :|.|.:.:|..:.|..:..||..:..:.|    :::|:.:|:..|..:..|.:    ||.||..|
Human    85 ALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNWAKLQRDYPDALITNYYL----WPAVQLAN 145

  Fly   144 FAFVPARNQVVFTSFFSMCWTTFLAY 169
            |..||...::......::.|.::|::
Human   146 FYLVPLHYRLAVVQCVAVIWNSYLSW 171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
plh	NP_649511.2	Mpv17_PMP22	107..168	CDD:461182	14/64 (22%)
MPV17	NP_002428.1	Mpv17_PMP22	109..170	CDD:461182	14/64 (22%)