DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc6 and BIRC6

DIOPT Version :9

Sequence 1:	NP_001246916.1	Gene:	Ubc6 / 40610	FlyBaseID:	FBgn0004436	Length:	151	Species:	Drosophila melanogaster
Sequence 2:	XP_005264507.2	Gene:	BIRC6 / 57448	HGNCID:	13516	Length:	4880	Species:	Homo sapiens

Alignment Length:	173	Identity:	51/173 - (29%)
Similarity:	81/173 - (46%)	Gaps:	27/173 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 STPARRRLMRDFKRLQEDPPTGVSGAP----TDNNIMIWNAVIFGPHDTPFEDGTFKLTIEFTEE 62
            |....|||.::...|....|...|.:.    .:..:.|...:|.||.|||:.:|.|:..:.|.::
Human  4594 SAARARRLAQEAVTLSTSLPLSSSSSVFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQD 4658

  Fly    63 YPNKPPTVRFV-----SKVFHPNVYADGGICLDIL-------QNRWSP-TYDVSAILTSIQSLL- 113
            ||:.||.|...     |..|:||:|.||.:||.||       :.:|:| |.....:|.|:|||:
Human  4659 YPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLIL 4723

  Fly   114 -SDPNPNSPA--NSTAAQLYKENRREYEKRVK------ACVEQ 147
             ::|..|.|.  .|.......::.|||:..::      |.:||
Human  4724 VAEPYFNEPGYERSRGTPSGTQSSREYDGNIRQATVKWAMLEQ 4766

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc6	NP_001246916.1	UQ_con	8..145	CDD:395127	47/163 (29%)
BIRC6	XP_005264507.2	BIR	287..360	CDD:237989
		DUF3643	3489..3641	CDD:289152
		UBCc	4620..4758	CDD:238117	41/137 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910