Protein Alignment Cdep and cora

DIOPT Version :10

• Sequence 1: NP_001097685.2
• Gene: Cdep / 40608
• FlyBaseID: FBgn0265082
• Length: 4273
• Species: Drosophila melanogaster
• Sequence 2: XP_061517000.1
• Gene: cora / 1280503
• VectorBaseID: AGAMI1_008137
• Length: 1677
• Species: Anopheles gambiae
• Alignment Length: 2090
• Identity: 434/2090 - (20%)
• Similarity: 706/2090 - (33%)
• Gaps: 680/2090 - (32%)

  Fly    57 TPSTPRHR--GGKKLTVRIQMLDDSITMFQVQAKALGRVLFEQVCRQLNLLEADYFGLEYQEVST 119
            :||||:.:  ..|....::.:||.||....:..|..||.|...||..||:||.|||||.|
Mosquito    16 SPSTPKKKPTNSKAALAKVTLLDGSILEVTIDRKCRGRDLLNSVCAGLNILEKDYFGLTY----- 75

  Fly   120 HT----KYWLDLEKPMNRQVGLSLIDP-VLRFCIKFYTPDPAQLEEEYTRYLFCLQIKRDLATGS 179
            ||    :.|||||:|:.:   ....|| .|.|.:|||.|:||||:|:.|||..|||::.|:..|.
Mosquito    76 HTANDPRTWLDLERPVTK---FFRSDPWDLSFEVKFYPPEPAQLQEDITRYHLCLQVRNDILEGR 137

  Fly   180 LQCNDNTAALMASYIVQASCGDFVPEDYPDHTYLSSYRFVPNQDATMQRKIMENHKKHVGQSPAE 244
            |.|:..|.||:.||:||:..||:.|.:..|.:||..::..|||...:..|:::.||.|..|:|||
Mosquito   138 LPCSFVTHALLGSYLVQSELGDYDPAEMKDRSYLKDFKIAPNQTPELLDKVIDLHKTHKSQTPAE 202

  Fly   245 ADLNLLETARRCELYGMKMHPAKDVEGVPLNLAVAHMGITVFQNITRINTFSWAKIRKISFKRKR 309
            |:|:.||.|::..:||:.:|||||.|||.:.|.|...|:.|:::..|||.|:|.||.|||:||..
Mosquito   203 AELHYLENAKKLAMYGVDLHPAKDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRNN 267

  Fly   310 FLVKLHPEGYGYYKDTVEFFFEGRNECKNFWKKCVENHGFFRCTAVQNTPRRKTRVLSR-GSSFR 373
            |.:|:.|..:..|:.|:.|..|.....|..||.|||:|.|||....:  |::|:.:..| ||.:|
Mosquito   268 FYIKIRPGEFEQYESTIGFKLENHRAAKKLWKACVEHHTFFRLMTPE--PQQKSGLFPRLGSKYR 330

  Fly   374 YSGKTQKQIIEFVRENYVKRQNFQRSQSFRQGPLNASSRSQSHTYVNSSISANPLLPIDTAAWDY 438
            |||:|          :|..|:.                                  |::..|.|:
Mosquito   331 YSGRT----------HYETRKT----------------------------------PVERPAPDF 351

  Fly   439 RNQCSDSMTPSLTKKAADTLDRRRDNPIGHMRSQVTAAQVEIYQTKNYAADSPTSQEEAECSAAG 503
            :.        |||.|...:            ||....||.|              :|.|....||
Mosquito   352 KR--------SLTGKRLSS------------RSMDALAQQE--------------KERAAAKDAG 382

  Fly   504 AERQHHSAVAMDKLNSNRSLSPQGPQSWTSPSHSSHHQQRGPDPARVHPGDHNTGLSHLSHLYSS 568
            .:           .|...::|                          ||.||...|
Mosquito   383 KD-----------ANKRHTMS--------------------------HPPDHIPDL--------- 401

  Fly   569 STPRRVSVGSQAFVPASPQLISINTPSSSTNHNTMHSTSTVVRSVDLNSSMELEEEAEDPGTADT 633
            .:|.|   ||::.:            ...........:||...|....||:|.|.|...|.....
Mosquito   402 DSPTR---GSRSPI------------KKDKKERLKRESSTGTASASSQSSLEGEYETTSPNVVPA 451

  Fly   634 EEEEGE----PV-GEEEEEELVEEEVDSDLTASTINRETMGAASAAAASASALGSGLASAHRPQL 693
            ::..|.    || |::::.|.|.:: |..|..:....|.:.:::..|.|.|....|..
Mosquito   452 QKPAGGVAVLPVAGKKDKPEQVSQK-DEGLNGNNGQAEALNSSAEEATSPSGKRKGFL------- 508

  Fly   694 RSQESQSLTATPVHYSSTNYSMSKQCMLNNANANSTETETDNIIYTDINDMGHYKYPDFHSSAHQ 758
                          :||...|..                       |..|.|:.:.....::|
Mosquito   509 --------------FSSGRKSPK-----------------------DKKDAGNEQPAKLMAAA-- 534

  Fly   759 EHKISNSEHLNLNERNDIYATVNRKAKSKIREKHFSDEFIDQSILQYTRAKQMGLSQVPVLLQQP 823
                 |.:..:..:::.....|..:|:.....|                              .|
Mosquito   535 -----NGDGGSAGKKDPAKEAVQARAQDTATNK------------------------------TP 564

  Fly   824 STSAYAAALQERSYNSGSYQYHNDLNHPSESSSSSYFGTGFGTKRYGQSERTKLAQSENYLTPSL 888
            .|:      .|:...:..|:|......|:.:...:....||   ||.::......:||..|:|
Mosquito   565 QTT------PEKPGFTKPYEYSESEQDPATAHKKNVKTRGF---RYDEAPLRPNEESEAQLSP-- 618

  Fly   889 DSQSSRHTHSLPRNSELSGVDSVDSYDSHYITHHSVGILPPGHLSSSSEKLDFQLPSGN---LYS 950
            :|||.|.| .|..|                        ..||......|.::.:...|:   ..:
Mosquito   619 NSQSRRAT-GLAFN------------------------YAPGEDQKVRESVEKRKAPGSPVAATA 658

  Fly   951 TTQFVKPEDAS----AHYMEDEEEEEE-----------DEGENIYDQVERDSWLKSSSCKDLF-- 998
            |...||.:..|    |..:..|.|.|:           ::|..:.|.:        :|....|
Mosquito   659 TAAGVKTDQLSPKSAARGLPGESEAEKGVRTSARSYSPNKGRQVVDPL--------ASGAGTFRP 715

  Fly   999 -ERYSSTYYDREH---------------SKPMTAFDKEFLSSNRIDSPVTRYDDSR----HSLYV 1043
             :..||.:...|.               ::|.....|..:..::.|....:.|.::    ||..|
Mosquito   716 LDDTSSAFIQGEQAGAAAAAAAAAAAAAAEPAKKKVKIMVIISKFDPKTKKVDTAQGVVEHSTGV 780

  Fly  1044 --AKNHSIDAHQGFSPLPQSKVYSSSYPGSTYNTQEHKRQHGHHMDYSGSQDDISQDSYELLEKY 1106
              .|...|::..|... |::        |:..|   ...:.|.:..:.|..|.         :..
Mosquito   781 LDTKTGQIESKYGLID-PKA--------GTVVN---FNARTGQNETFQGQTDP---------KTG 824

  Fly  1107 DIDFFGG-----RGRSEDHMRSCSLDSGNYIPSDDESVSEGHQQHKYRSEMDVKSKSAADIMNEI 1166
            .:...||     .|:.:|     :|.....:..|::||.|   .....|::|..:.....|..||
Mosquito   825 QLHIVGGVVDSASGKVDD-----TLGQAIMVVPDEDSVVE---ITTITSKVDPNTGKIDTINGEI 881

  Fly  1167 WDAEDPRYLPREKLSVKSDGNFYKKIQEALVRTSSLESQSEMFETKISRSSDSSKKSRDSLYHTD 1231
               |..|.:...:..:.|     .|..:...||..|.:    .:.|..:.|.::...|..   |.
Mosquito   882 ---EKSRGILNHRTGILS-----TKYGDINPRTGELRA----IDPKTGKPSPAAAAVRPV---TV 931

  Fly  1232 SKKSRE-----TTKSKTSVASSQDSKESLVGDCFGRNYEMPTTTGKKVKQFTKKELYEKFAQSSQ 1291
            .:.:.:     .|..||:...:..:....:|:......|:.:..||    ..||.|.
Mosquito   932 DRSNGQIMVVGVTDPKTNKLDNSQAHLIAIGNQVDPVVEVTSVLGK----LDKKGLV-------- 984

  Fly  1292 ESKSDYYDAVETGLEHTPEGLYSRPKVKSHDCLLSDTHSSTANSSFYDSRDTYS---TFPSNKTH 1353
            :.|:..||. .||...|.:|     |:.:.                |...|...   ||...||.
Mosquito   985 DPKTITYDK-STGQLDTKDG-----KINTK----------------YGQLDLVKQTVTFVDPKTG 1027

  Fly  1354 KTS----KVHSISLQ-------NVEIERNAKSFGS----KSPESVSTPASGKRCREKDIQTGDSL 1403
            ||.    ||..:|.|       |.:..:..|.:|.    :...:...|.:||..
Mosquito  1028 KTETKEIKVDPVSGQVLLKNQVNPKTGKTDKDYGRIVSIRIVHNRIDPVTGKHV----------- 1081

  Fly  1404 DQMAPIKRGNSQSCKISAFRRRSDSENIFSFDQD-RIECIQKYTKQWEGQQPKDEK--------S 1459
             ..||::                        |:| |::.  |..:.|.....||.|        |
Mosquito  1082 -PAAPVE------------------------DKDIRVDA--KTNQVWLPDGGKDPKTGETIYTSS 1119

  Fly  1460 KQSPE-------YPLTPELVSEFEKQQARLMAHQKITRKEELIAKTHFEEYNPIMVPLN------ 1511
            :..|:       |.......:|.|:|                      .:.:|.|..::
Mosquito  1120 QVDPKTGFVITIYGYLNPKTNEIERQ----------------------AKMDPNMTKVDPTTGQI 1162

  Fly  1512 YSSHATVERTKSDPNSLANR------------ARLGSNSRRHVLMHQKSIDLTPADSNSSDED-- 1562
            |::...|:.|..:|...|.:            .|:...|.|.|::  |...:|..|.....|:
Mosquito  1163 YAATGQVDETTGEPLFAATQINEEDGEIYTKVGRIDPKSGRLVII--KIFIITKKDERGKPEELD 1225

  Fly  1563 ---------------------YIYKQ-----------IPSAPPLCKAHGNFEIPKCYDGS---AA 1592
                                 |:||.           .|:.|.:..|...........|.   |.
Mosquito  1226 VSAVDLDPETGHIRNIAPKTLYLYKMRDPITGETYNVDPNDPRIAGARTTVTQTMTLSGEIDPAT 1290

  Fly  1593 SQIAQEL----PKTGFELPKSFFRD-----------------YERRFTKVLKEDIPYVLHK---- 1632
            .:|..|.    |.||...|.:..||                 :.:..| |.||.:|....:
Mosquito  1291 GRIKSEWGHIDPNTGDIDPATAIRDPVTGKLILNYADIEPSHFGKNVT-VTKETVPITREQFYEG 1354

  Fly  1633 -RHIMNGTAPSPSEKKHTKPKSPKSPKSPKSPKSPKSPKSPKASSGGLGPGSTDFLPDILDSLLP 1696
             :|:         ::|.|:..|..|.....:....:|.|  :.|||....||.........:...
Mosquito  1355 IKHM---------DRKATRRDSESSDDDMTAQYGKESIK--EISSGTAAAGSKLNAAAAAAAAAG 1408

  Fly  1697 SDTKEFLFTQNIDLSKVDPITLEIDKTIPTI-------HLSSPKRDITKQMDAS---TLEKLNKK 1751
            :.|.....|:.:.....|.:|..:::.:..:       .....|.|.....||.   |...:..:
Mosquito  1409 TPTVVKTTTKQVITKNEDGVTHNVEEEVQNLGTGQIVYSTQEHKADAPTGTDAGKFVTATAVTTR 1473

  Fly  1752 LSQIESDSATSSRTESMQQQKLEQKQMELIQSLRKELQANARKANKPRVIPK------TKSAGKS 1810
            .:....|..|:::|     |:||:|.:....:...|.|       :.|||.:      |.::|..
Mosquito  1474 TATTHEDLGTNAKT-----QQLEEKTVATTTTQHGERQ-------EQRVITQEVKTTATVTSGDQ 1526

  Fly  1811 KKGKTRITSFSS-----------DDESLD----------SDDVFGSAEAIPDRLEFSPPQSRKEI 1854
            ...:..::|.||           .||||.          :|:|.|::: ||:    .|
Mosquito  1527 YARRDSVSSSSSGDSGTPIDGPYGDESLSEVIYNKSYTGADNVVGASQ-IPE----GP------- 1579

  Fly  1855 ESILRIEQSRLISAAWGRGQTMSSTEIEGSPPQCRRLADLES-RYHTQKLDPQYANATELRRISE 1918
                .:|..|::......|.|.:..||..|.....:...:|: .|.|::     ....|.|  .|
Mosquito  1580 ----NVEHRRVVLDDLAEGGTTTHGEIVSSQTVSSKTRTVETITYKTER-----DGVVETR--VE 1633

  Fly  1919 RSISIPSSED 1928
            :.|:|.|..|
Mosquito  1634 QKITIQSDGD 1643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdep	NP_001097685.2	B41	70..264	CDD:214604	82/198 (41%)
		FERM_C_FARP1-like	251..372	CDD:270014	50/121 (41%)
		FA	364..404	CDD:462582	10/40 (25%)
		GAPT	<1240..1299	CDD:463345	10/58 (17%)
		PTZ00121	<2219..2716	CDD:173412
cora	XP_061517000.1	None