Protein Alignment Gnf1 and rfc1

DIOPT Version :9

• Sequence 1: NP_001014605.1
• Gene: Gnf1 / 40607
• FlyBaseID: FBgn0004913
• Length: 1008
• Species: Drosophila melanogaster
• Sequence 2: NP_001186496.1
• Gene: rfc1 / 733476
• XenbaseID: XB-GENE-964734
• Length: 1144
• Species: Xenopus tropicalis
• Alignment Length: 1170
• Identity: 447/1170 - (38%)
• Similarity: 618/1170 - (52%)
• Gaps: 229/1170 - (19%)

  Fly    15 KAKSAE--AENGETPSKAP-----------KRRKAVIISSDEDEVVSPPETKKRKASKTASSEDD 66
            |.||:|  .::.:...|:|           |::|.:|..||.:|...|.:..||.:.|:......
 Frog    26 KKKSSEEIKKSKDIKVKSPSSDDSSKGMHVKKKKRIIYDSDAEEETPPVKKAKRPSEKSPPRPRP 90

  Fly    67 VVAATPEPIA-------------KKAR----NG-------------------QKPALSKLKRHVD 95
            ...:.|:|:.             ||:|    ||                   :||...:.|....
 Frog    91 NKISKPDPVVFVSDTDEEDFDQKKKSRKPKENGTSTVHSERPQVPAKVPAAQRKPVTPEKKNPAC 155

  Fly    96 PTELFGGET-----KRVIVPKPK----------------TKAVLEFENEDIDRSLMEVD------ 133
            ..:.||..:     |:::..|.|                .|.:...|:.:::|.|.|.:
 Frog   156 LEDFFGMNSVKRSDKKLVASKRKAPCESSGDSTQDDESIAKQLQLEEDAELERQLHEDEEFARTL 220

  Fly   134 --LDESIKEAAPE--KKVHSIT-RSSP------------SPKRAK-------------------- 161
              |||:.|....:  :|:.|:| :.||            .|:|||
 Frog   221 AMLDEAPKNTQKKTGEKLASLTSKKSPMKVEKNEKHSHSPPERAKSLSDEWKGSKARDHMKADHK 285

  Fly   162 ---------------NSSPEPP------------KPKSTKSKATTPRVKKEKPAADLESSVLTDE 199
                           :||.|.|            |.::.|.:.::|.:|.||.:...|.|  |.|
 Frog   286 KPCLSESSSGHLTKSSSSKESPLKASSKLALMKQKDEAAKQQKSSPEMKVEKISPKKEQS--TPE 348

  Fly   200 ----------ERHERKRASAVLYQKYKNRSSCLNPGSKEIPKGSPDCLSGLTFVVTGVLESMERE 254
                      |..|:||.:...|:.:.||......||||||.|:.:|:.|||||:||||||:||:
 Frog   349 KSPQKTGSSPEDSEKKRTNYKAYRNFLNREGPKALGSKEIPIGADNCMEGLTFVITGVLESIERD 413

  Fly   255 EAESVIKEYGGKVMTVVGKKLKYLVVGEEAGPKKLAVAEELNIPILSEDGLFDLI------REKS 313
            ||:|:::.|||||...|.||..|:::|.:||..|...||.....||.||||.:||      |.|.
 Frog   414 EAKSLVERYGGKVTGNVSKKTNYIIMGRDAGVSKQEKAEAFGTKILDEDGLLNLIRTLPGKRSKY 478

  Fly   314 GIAKQVKEEKKSPKKEHSSEEKGKKEVKTSRRSSDKKEKEATKLKYGEKHDIAKHKVKEEHTSPK 378
            .||...:.:|...|.|.|.:   |||..|.:..:.:|:::.:|.....|......|.:..|.:..
 Frog   479 DIAAAAEAKKAKIKTEKSPD---KKEPLTKKTVTPEKKEQTSKKPSPAKRRFTPEKKESSHKTDL 540

  Fly   379 ETKDKLNDVPAVTLKVKKEPSSQKEHPPSPRTADLKTLDVVGMAWVDKHKPTSIKEIVGQAGAAS 443
            ..|.|       |..|||||   :|..|:....||:   ...:.||||:||||||:|:||.|..|
 Frog   541 NEKVK-------TKVVKKEP---EELEPTTTDGDLQ---CESLLWVDKYKPTSIKQIIGQQGEQS 592

  Fly   444 NVTNHNLKLKAKQERVKVLHYFNFPRLMNWLSKWYVNHDGN-KKP-QRPNPWAKNDDGSFYKAAL 506
            ...                      :||.||::|:.||..: ||| .:.|.:...||||.:||||
 Frog   593 CAN----------------------KLMKWLNRWHQNHSSDEKKPAAKLNKFGGKDDGSSFKAAL 635

  Fly   507 LSGPPGIGKTTTATLVVKELGFDAVEFNASDTRSKRLLKDEVSTLLSNKSLSGYFTGQGQAVSRK 571
            ||||||:||||||.||.:|||:..||.||||||||..:|:.|:..|:|.|:.|:::|..::||.|
 Frog   636 LSGPPGVGKTTTAVLVCEELGYSYVELNASDTRSKNSMKEVVAESLNNTSIKGFYSGTCKSVSSK 700

  Fly   572 HVLIMDEVDGMAGNEDRGGMQELIALIKDSSIPIICMCNDRNHPKIRSLVNYCYDLRFQRPRLEQ 636
            |.||||||||||||||||||||||.|||.|.||||||||||||.|||||.|||:||||||||:||
 Frog   701 HALIMDEVDGMAGNEDRGGMQELITLIKQSKIPIICMCNDRNHSKIRSLANYCFDLRFQRPRVEQ 765

  Fly   637 IKGKIMSICFKEKVKISPAKVEEIIAATNNDIRQSINHIALLSAKEDA----SQKSGQQVATKDL 697
            |||.:||:.|||.:||.|..:.|||...|.||||.::::::..|:..|    ..||....|.||:
 Frog   766 IKGAMMSVAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDEAKSSATNAKKDI 830

  Fly   698 KLGPWEVVRKVFTA-DEHKHMSFADKSDLFFHDYSLAPLFVQQNYLQVLPQ---GNKKDVLAKVA 758
            |:||::||||||:: :|..||:..||||||||||||||||||:||:.|.|.   ||.|..|..::
 Frog   831 KMGPFDVVRKVFSSGEETAHMTLIDKSDLFFHDYSLAPLFVQENYVHVKPAAAGGNMKKHLLLLS 895

  Fly   759 ATADALSLGDLVEKRIRANSAWSLLPTQAFFSSVLPGEHMCGHFTGQI-NFPGWLGKNSKSGKRA 822
            ..||::..||||::.||:...||||||||.::||||||.|.| :.||. |||.||||.|.:||..
 Frog   896 KAADSICDGDLVDRMIRSKQTWSLLPTQAVYASVLPGELMRG-YMGQFPNFPSWLGKYSSTGKYD 959

  Fly   823 RLAQELHDHTRVCTSGSRLSVRLDYAPFLLDNIVRPLAKDGQEGVPAALDVMKDYHLLREDLDSL 887
            |:.|||..||.:.|..::.::.|||..::.|.:||||.:.|.:||...:|.|.:|:|::||.|::
 Frog   960 RITQELTMHTCLRTRTNKGALNLDYLSYVRDVLVRPLHQSGADGVGEVVDFMDNYYLMKEDYDNI 1024

  Fly   888 VELTSWPGKKSPLDAVDGRVKAALTRSYNKEVMAYSYSAQAGIKKKKSEAAGADDDYLDEGPGEE 952
            :|::.|.||.|....:|.:||||.||.||||.....||.|. :|..|..||.|.:..|.|.|..|
 Frog  1025 MEISCWGGKPSAFSKLDPKVKAAFTRGYNKEAHLTPYSLQM-VKASKRAAASAAESELSEEPNNE 1088

  Fly   953 DGAGGHLSSEEDEDKDNLELDSLIKAKK---------RTTTSKASGGSKKATSSTASKSKAKAKK 1008
            :     .:.|.:|..:::|||::|||||         ..|.....||.||      ...|||:||
 Frog  1089 E-----QNEETEEQGEDVELDAMIKAKKAKQAKPAKPAKTAKTEKGGEKK------PPGKAKSKK 1142

  Fly  1009  1008
             Frog  1143  1142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gnf1	NP_001014605.1	COG5275	<151..358	CDD:227600	89/282 (32%)
		BRCT	232..309	CDD:278934	39/76 (51%)
		PRK04195	421..969	CDD:235250	283/558 (51%)
		AAA	506..633	CDD:278434	91/126 (72%)
		RFC1	764..917	CDD:285691	72/153 (47%)
rfc1	NP_001186496.1	COG5275	260..523	CDD:227600	86/267 (32%)
		BRCT	398..469	CDD:237994	38/70 (54%)
		AAA	635..764	CDD:214640	93/128 (73%)
		AAA	635..762	CDD:278434	91/126 (72%)
		RFC1	901..1054	CDD:285691	72/153 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	161	1.000	Domainoid score	I3981
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2187
Inparanoid	1	1.050	687	1.000	Inparanoid score	I689
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291910at33208
OrthoFinder	1	1.000	-	-		FOG0003699
OrthoInspector	1	1.000	-	-		oto105383
Panther	1	1.100	-	-	LDO	PTHR23389
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3601
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160