Protein Alignment Gnf1 and rfc-1

DIOPT Version :9

• Sequence 1: NP_001014605.1
• Gene: Gnf1 / 40607
• FlyBaseID: FBgn0004913
• Length: 1008
• Species: Drosophila melanogaster
• Sequence 2: NP_001256606.1
• Gene: rfc-1 / 179967
• WormBaseID: WBGene00004337
• Length: 839
• Species: Caenorhabditis elegans
• Alignment Length: 987
• Identity: 309/987 - (31%)
• Similarity: 472/987 - (47%)
• Gaps: 214/987 - (21%)

  Fly    54 KRKASKTASSEDDVVAATPEPIAKKARNGQKPALSKLKRHVDPTELFGGETKRVIVPKPKT--KA 116
            |||...::.|:||:      |..::.   ||.|.:..|:...|..|...:.:....|:.||  |.
 Worm     4 KRKIVVSSDSDDDM------PFTQEK---QKKAATPAKKRTKPVVLTDDDEEEENAPQKKTAPKR 59

  Fly   117 VLEFENEDIDRSLMEVDLDESIKEAAPEKKVHSITRSSPSPKRAKNSSPEPP----------KPK 171
            ..:.|.|:.|   :..|.||             :.|.:...|:.|....|.|          ||.
 Worm    60 SRKQEKEESD---ITSDEDE-------------LVRGTDEKKKRKGGKKELPVGQKTLDYMFKPS 108

  Fly   172 STKSKATTPRVKKEKP---AADLESSVLTDEERHERKRASAVLYQKYKNRSSCLNPGSKEIPKGS 233
            |:.||...|:.|.||.   .||.                       :||..:   |.:.::||.:
 Worm   109 SSSSKRDDPKKKVEKTLVNPADF-----------------------FKNSPA---PSASKLPKVA 147

  Fly   234 PDCLSGLTFVVTGVLESMEREEAESVIKEYGGKVMTVVGKKLKYLVVGEEAGPKKLAVAEELNIP 298
            |              :::|:.:..:       |....:....|     |....||::..|
 Worm   148 P--------------KTVEKPKTPA-------KKPVEISPSTK-----ENTKTKKVSDDE----- 181

  Fly   299 ILSEDGLFDLIREKSGIAKQVKEEKKSPKKEHSSEEKGKKEVKTSRRSSDKKEKEATKLKYGEKH 363
            .:..|..||..       ..:..:||:|:|        :||      :..|||..:.|.::.:|.
 Worm   182 FVDSDDSFDTF-------TPITVKKKTPEK--------RKE------TPKKKELPSVKKEFPKKQ 225

  Fly   364 DIAKHKVKEEHTSPKETKDKLNDVPAVTLKVKKEPSSQKEHPPSPRTADLKTLDVV--------- 419
            .|   .||:|    |||..|      ..|.|||:|  .|....|..::.:.|..||
 Worm   226 SI---PVKKE----KETPQK------KALSVKKDP--PKVTSESSSSSQVSTSSVVFQPKPSGPP 275

  Fly   420 -GMAWVDKHKPTSIKEIVGQAGAASNVTNHNLKLKAKQERVKVLHYFNFPRLMNWLSKWYVNHDG 483
             .::||||:||..:.|:|||.|..|.:.                      :|:.|:..|..::.|
 Worm   276 PALSWVDKYKPKRMGELVGQNGDKSPIN----------------------KLLEWIKDWAKHNLG 318

  Fly   484 N----KKPQRPNPWAKNDDGSFYKAALLSGPPGIGKTTTATLVVKELGFDAVEFNASDTRSKRLL 544
            .    ||| :|.||..:.||:.:|||||||.||:||||.|.:..::||...||.||||.|||:.|
 Worm   319 EGAKIKKP-KPAPWMSSQDGTSFKAALLSGSPGVGKTTCAYMACQQLGLQLVEMNASDVRSKKHL 382

  Fly   545 KDEVSTLLSNKSLSGYFTGQ------GQAVSRKHVLIMDEVDGMAGNEDRGGMQELIALIKDSSI 603
            :.::..|..:..:..:|..:      .|.|  .|:|||||||||:|||||.|:.|||.:||:|.|
 Worm   383 EAKIGELSGSHQIEQFFGAKKCAPQDNQKV--HHILIMDEVDGMSGNEDRAGISELIQIIKESKI 445

  Fly   604 PIICMCNDRNHPKIRSLVNYCYDLRFQRPRLEQIKGKIMSICFKEKVKISPAKVEEIIAATNNDI 668
            ||||:||||.|||||:|.||||||||.:||:|.|:.::|:||.:||:||...:::|||..:.:|:
 Worm   446 PIICICNDRQHPKIRTLANYCYDLRFPKPRVETIRSRMMTICSQEKMKIGKEELDEIIELSGHDV 510

  Fly   669 RQSINHIALLSAKEDASQKSGQQVATKDLKLGPWEVVRKVFTADEHKHMSFADKSDLFFHDYSLA 733
            ||:|.::.:      .|:..|.::..||:.:..:...|::..:    ..:..:|.::||.||.:.
 Worm   511 RQTIYNLQM------RSKGVGAKINQKDMAVDAFSAARRLLDS----RTTLMEKQEMFFTDYGIM 565

  Fly   734 PLFVQQNYLQVLPQGNKK----DVLAKVAATADALSLGDLVEKRIRANSAWSLLPTQAFFSSVLP 794
            |||||.|||.:   .|:|    ..:..:...||.:|||||::::||...:|.||..|:..|:.||
 Worm   566 PLFVQDNYLNM---KNEKHSPIQAIRGIRKAADFISLGDLIDRQIRGGGSWKLLNEQSMISAALP 627

  Fly   795 GEHMCGHFTGQINFPGWLGKNSKSGKRARLAQELHDHTRVCTSGSRLSVRLDYAPFLLDNIVRPL 859
            .....||....|.||.||||||.:|||.||.|:|..||.:..|....|...||||.|...|.:||
 Worm   628 AIATGGHLKAMIQFPSWLGKNSTAGKRKRLLQQLVQHTHLKVSAGTHSFATDYAPMLRQKITKPL 692

  Fly   860 AKDGQEGVPAALDVMKDYHLLREDLDSLVELTSWPGKKSPLDAVDGRVKAALTRSYNK--EVMAY 922
            .:...:|:|..:..|.:|.|:::|.::|.|:.:||||..|...:..:|||:|||:.||  .::.|
 Worm   693 LEHEADGIPDVISTMTEYDLIKDDTEALTEIVAWPGKIDPASKILSKVKASLTRTLNKTGRMLPY 757

  Fly   923 SYSAQAGIKKKKSEAAGADDDYLDEGP-----GEEDGAGGHLSSEEDEDKDNLELDSLIKAKKRT 982
            |..:.:..||:...:.|.:.|  :||.     .:|||      ..::||.:....|.:||.:
 Worm   758 SMDSVSKGKKRGVNSIGIEMD--EEGNLVEKFEDEDG------ESDNEDNEEKTTDVVIKVR--- 811

  Fly   983 TTSKASGGSKKA 994
             |...:|.||.|
 Worm   812 -TGGGAGASKSA 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gnf1	NP_001014605.1	COG5275	<151..358	CDD:227600	42/219 (19%)
		BRCT	232..309	CDD:278934	11/76 (14%)
		PRK04195	421..969	CDD:235250	217/568 (38%)
		AAA	506..633	CDD:278434	72/132 (55%)
		RFC1	764..917	CDD:285691	63/152 (41%)
rfc-1	NP_001256606.1	PRK04195	277..805	CDD:235250	217/573 (38%)
		AAA	344..453	CDD:278434	55/110 (50%)
		RFC1	597..750	CDD:285691	63/152 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165716
Domainoid	1	1.000	139	1.000	Domainoid score	I2984
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	435	1.000	Inparanoid score	I947
Isobase	1	0.950	-	0	Normalized mean entropy	S1907
OMA	1	1.010	-	-		QHG52880
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003699
OrthoInspector	1	1.000	-	-		oto17794
orthoMCL	1	0.900	-	-		OOG6_101059
Panther	1	1.100	-	-	LDO	PTHR23389
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1087
SonicParanoid	1	1.000	-	-		X3601
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.880