| Sequence 1: | NP_001368991.1 | Gene: | opa / 40605 | FlyBaseID: | FBgn0003002 | Length: | 688 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_009060.2 | Gene: | ZIC2 / 7546 | HGNCID: | 12873 | Length: | 532 | Species: | Homo sapiens |
| Alignment Length: | 529 | Identity: | 220/529 - (41%) |
|---|---|---|---|
| Similarity: | 269/529 - (50%) | Gaps: | 129/529 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 4 NAFIEPAQHHLASYGL-----RMSPNTTASNSNAQQQQQQQLEMTQQQQQQQQQQQQQQQQDQES 63
Fly 64 AAATAAAYQNSGYGHFNSY------ASRDFLLGRR--------EAEYGV--AGSAGQASAAADS- 111
Fly 112 --MLFSGFPAQAAELGS----------GFGQHPFHSHHHHHQMRMGMADAYAAGHPYNHHG---- 160
Fly 161 ----NFPTAAVHHPVVHHPSHHAMSAMHPAGAGAFLRYMRHQPASSASSVKQEMQCLWIDPDQPG 221
Fly 222 LVPPGGRKTCNKVFHSMHEIVTHLTVEHVGGPECTTHACFWVGCSRNGRPFKAKYKLVNHIRVHT 286
Fly 287 GEKPFACPHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKHSHVHTSDKPY 351
Fly 352 NCRINGCDKSYTHPSSLRKHMKVHGNVDEKSPSHGYDSEGEESSS-SSIITGGAQTPPSTRL--- 412
Fly 413 -------------------------DGSAGSSSGVSSLSGGSGIKSSPHSIKSEPNPMHSVHLGA 452
Fly 453 SSSGSSSTA 461 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| opa | NP_001368991.1 | zf_ZIC | 206..253 | CDD:408166 | 27/46 (59%) |
| C2H2 Zn finger | 265..285 | CDD:275368 | 16/19 (84%) | ||
| SFP1 | <287..373 | CDD:227516 | 75/85 (88%) | ||
| C2H2 Zn finger | 293..315 | CDD:275368 | 20/21 (95%) | ||
| C2H2 Zn finger | 323..345 | CDD:275368 | 19/21 (90%) | ||
| C2H2 Zn finger | 353..375 | CDD:275368 | 17/21 (81%) | ||
| ZIC2 | NP_009060.2 | Necessary for interaction with MDFIC and transcriptional activation or repression. /evidence=ECO:0000250 | 100..255 | 48/171 (28%) | |
| zf_ZIC | 250..295 | CDD:408166 | 28/54 (52%) | ||
| C2H2 Zn finger | 307..327 | CDD:275368 | 16/19 (84%) | ||
| SFP1 | <329..413 | CDD:227516 | 75/85 (88%) | ||
| C2H2 Zn finger | 335..357 | CDD:275368 | 20/21 (95%) | ||
| C2H2 Zn finger | 365..387 | CDD:275368 | 19/21 (90%) | ||
| C2H2 Zn finger | 395..415 | CDD:275368 | 17/21 (81%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 406..452 | 19/45 (42%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 475..532 | 17/56 (30%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 68 | 1.000 | Domainoid score | I9708 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BCH8 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 341 | 1.000 | Inparanoid score | I2358 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000467 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41195 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR19818 |
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4702 |
| SonicParanoid | 1 | 1.000 | - | - | X217 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 9 | 9.080 | |||||