Protein Alignment opa and zic6

DIOPT Version :10

• Sequence 1: NP_001368991.1
• Gene: opa / 40605
• FlyBaseID: FBgn0003002
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001001837.1
• Gene: zic6 / 415097
• ZFINID: ZDB-GENE-061207-1
• Length: 525
• Species: Danio rerio
• Alignment Length: 406
• Identity: 168/406 - (41%)
• Similarity: 211/406 - (51%)
• Gaps: 76/406 - (18%)

  Fly    68 AAAYQNSGYGHF--NSYAS-------RDFLLGRREAEYGVAGSAGQASAAADSMLFSGFPAQAAE 123
            |:||.:....||  ..|.|       |..::|...:..|:.....|.::.         |.|...
Zfish    60 ASAYVDHSVTHFPDTGYTSHRLEPSPRGIIIGTNLSAAGMPPVTDQLASR---------PTQHGN 115

  Fly   124 LGSGFGQHPFHSHHHH---------------------HQMRMGM-ADAYAAGHPYNHHGNFPTAA 166
            :|.....|.:.....|                     .||.:|: .|..:..|||....:.|.|.
Zfish   116 IGRYRDLHSYRDGRSHAFFTAYQEQAHGSSDATRDLSSQMMLGLPGDLLSRTHPYGQPVSGPRAN 180

  Fly   167 VHHPVV-----HHPSHHAMSAMHPAGAGAFLRYMRHQPASSASSVKQEMQCLWIDPDQPGLVPPG 226
            ....|.     :.|.:   .||...|..||||..|..|       |.|:.|.|.| .|.|.
Zfish   181 SQQLVTQFLEFYKPLN---MAMQRGGGDAFLRCSRQNP-------KHELVCKWSD-GQEGT---- 230

  Fly   227 GRKTCNKVFHSMHEIVTHLTVEHVGGPECTTHACFWVGCSRNGRPFKAKYKLVNHIRVHTGEKPF 291
            |:..|.:.|.:|:|:|||:|||||||||.:.:.|.|..|.|:.:|||||||||||:|||||||||
Zfish   231 GKPPCARSFGTMYELVTHVTVEHVGGPEHSDYVCHWENCPRDRKPFKAKYKLVNHVRVHTGEKPF 295

  Fly   292 ACPHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKHSHVHTSDKPYNCRIN 356
            .||..||.|||||||||||||||||||||||||.|||:||||||||||||||||:|||||.|::.
Zfish   296 PCPFHGCEKVFARSENLKIHKRTHTGEKPFKCEFEGCNRRFANSSDRKKHSHVHSSDKPYTCKVR 360

  Fly   357 GCDKSYTHPSSLRKHMKVH--------GNVDE-----KSPSHGYDSEGEESSSSSIITGGAQTPP 408
            ||:|.||||||||||||:|        |..||     :||.   .:|.:::.:|:.:|....||.
Zfish   361 GCEKCYTHPSSLRKHMKLHCKAYIAKIGEDDEHLVEARSPE---VTEHQDTPASTTVTRTMTTPS 422

  Fly   409 STRLDGSAGSSSGVSS 424
            ...|.....:.|.|.|
Zfish   423 HETLSPETRNESAVRS 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
opa	NP_001368991.1	zf_ZIC	206..253	CDD:436441	21/46 (46%)
		C2H2 Zn finger	265..285	CDD:275368	14/19 (74%)
		SFP1	<287..373	CDD:227516	72/85 (85%)
		C2H2 Zn finger	293..315	CDD:275368	18/21 (86%)
		C2H2 Zn finger	323..345	CDD:275368	19/21 (90%)
		C2H2 Zn finger	353..375	CDD:275368	16/21 (76%)
zic6	NP_001001837.1	zf_ZIC	213..257	CDD:436441	22/55 (40%)
		C2H2 Zn finger	269..289	CDD:275368	14/19 (74%)
		SFP1	<291..377	CDD:227516	72/85 (85%)
		C2H2 Zn finger	297..319	CDD:275368	18/21 (86%)
		C2H2 Zn finger	327..349	CDD:275368	19/21 (90%)
		C2H2 Zn finger	357..379	CDD:275368	16/21 (76%)