Protein Alignment opa and zic5

DIOPT Version :9

• Sequence 1: NP_001368991.1
• Gene: opa / 40605
• FlyBaseID: FBgn0003002
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_991290.1
• Gene: zic5 / 403041
• ZFINID: ZDB-GENE-040622-1
• Length: 497
• Species: Danio rerio
• Alignment Length: 528
• Identity: 219/528 - (41%)
• Similarity: 263/528 - (49%)
• Gaps: 124/528 - (23%)

  Fly     3 MNAFIEPAQHHLASYGLRMSPNTTASNSNA--------QQQQQQQLEMTQQQQQQQQQQQQQQQQ 59
            |..|.....||..|:...:.|....::...        ...|...|:::..|..|...:.|
Zfish    28 MTGFPGIGGHHPHSHHAHLHPGEMGNDPGVALTPFGPEHMAQTNALKLSPSQPVQSHPEAQ---- 88

  Fly    60 DQESAAATAAAYQNS--------GYGHFNSYASRDFLLGRREAEYGVAGSAGQASAAADSMLFSG 116
                   |||::.:|        .:.|.....||||:| |||.......:.|...::|.|....|
Zfish    89 -------TAASFTSSQTTVGFPVAHPHTGYTTSRDFIL-RRELSASAMHALGDQHSSASSPHHHG 145

  Fly   117 F---PAQAAELGSGFGQHPFHS----------HHHHH----QMRMGM-ADAYAAGHPYNHHGNFP 163
            .   |..|.....| |.||..|          |||||    |||:|: .|.|  |.| .|.|
Zfish   146 MFISPTGAYGHAEG-GAHPLFSGLHEQAAPGAHHHHHALNGQMRLGLPGDIY--GRP-EHFG--- 203

  Fly   164 TAAVHHPVVHHPSHHAMSAMH--------------PAGA-GAFLRYMRHQPASSASSVKQEMQCL 213
                     |.|.|:..|::|              |.|| |||||||| ||      :|||:.|.
Zfish   204 ---------HRPEHYGSSSLHSYNSMNLNVNLATAPHGATGAFLRYMR-QP------IKQELICK 252

  Fly   214 WIDPDQPGLVPPGGRKTCNKVFHSMHEIVTHLTVEHVGGPECTTHACFWVGCSRNGRPFKAKYKL 278
            |||.:|.      .:|.|:|.|.:|||:|.|:|||||||||.:||.|||..|.|.|:.|||||||
Zfish   253 WIDQEQT------AKKPCSKTFSTMHELVNHVTVEHVGGPEQSTHVCFWEECPREGKAFKAKYKL 311

  Fly   279 VNHIRVHTGEKPFACPHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKHSH 343
            :||||||||||||.||.|||||||||||||||||||||||||||||.:||||:||||||||||||
Zfish   312 INHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSH 376

  Fly   344 VHTSDKPYNCRINGCDKSYTHPSSLRKHMKVHGNVDEKSPSHGYDSEGEESSSSSIITGGAQTPP 408
            ||||||||.|::.|||||||||||||||||||.    |||.....:.|.....||...|.|.:|
Zfish   377 VHTSDKPYFCKVRGCDKSYTHPSSLRKHMKVHC----KSPPPPSANTGSSYHPSSTTIGDALSP- 436

  Fly   409 STRLDGSAGSSSGVSS----------LSGGSGIKSSPHSIKSEPNPMHSVHLGASSSGSSSTASS 463
              .||.....||.:|.          ..|.:|           ||.:|      :.|....|:.|
Zfish   437 --NLDPHRNRSSNLSPQVTNLNEWYVCQGSAG-----------PNNLH------TPSSDVPTSES 482

  Fly   464 SASHLLQH 471
            ......:|
Zfish   483 DDEDSFRH 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
opa	NP_001368991.1	zf_ZIC	206..253	CDD:408166	23/46 (50%)
		C2H2 Zn finger	265..285	CDD:275368	14/19 (74%)
		SFP1	<287..373	CDD:227516	76/85 (89%)
		C2H2 Zn finger	293..315	CDD:275368	20/21 (95%)
		C2H2 Zn finger	323..345	CDD:275368	18/21 (86%)
		C2H2 Zn finger	353..375	CDD:275368	18/21 (86%)
zic5	NP_991290.1	C2H2 Zn finger	298..318	CDD:275368	14/19 (74%)
		zf-H2C2_2	311..337	CDD:290200	22/25 (88%)
		zf-C2H2_8	325..407	CDD:292531	72/81 (89%)
		C2H2 Zn finger	326..348	CDD:275368	20/21 (95%)
		zf-H2C2_2	340..367	CDD:290200	23/26 (88%)
		C2H2 Zn finger	356..378	CDD:275368	18/21 (86%)
		C2H2 Zn finger	386..408	CDD:275368	18/21 (86%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8803
eggNOG	1	0.900	-	-		E33208_3BCH8
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	338	1.000	Inparanoid score	I2344
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D268347at33208
OrthoFinder	1	1.000	-	-		FOG0000467
OrthoInspector	1	1.000	-	-		otm24928
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19818
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X217
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	9.060