Protein Alignment opa and zic3

DIOPT Version :10

• Sequence 1: NP_001368991.1
• Gene: opa / 40605
• FlyBaseID: FBgn0003002
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001001950.1
• Gene: zic3 / 368263
• ZFINID: ZDB-GENE-030708-2
• Length: 448
• Species: Danio rerio
• Alignment Length: 465
• Identity: 199/465 - (42%)
• Similarity: 256/465 - (55%)
• Gaps: 86/465 - (18%)

  Fly     3 MNAFIEPAQHHLASY--GLRMSPNTTASNSNAQQQQQQQLEMTQQQQQQQQQQQQQQQQDQESAA 65
            :..|..|..|.|.:.  ||.:||...:|:|.|.:......::...|......|          |.
Zfish    16 VGGFGTPRHHELGNRDPGLGLSPFADSSHSAAFKISPVTHDIASSQTSAFTPQ----------AT 70

  Fly    66 ATAAAYQNSGYGHFNSYA------SRDFLLGRR----------EAEYGV-AGSAGQ------ASA 107
            ..|||..:...|...|||      :||||...|          .|::|: |.|||.      .|.
Zfish    71 GYAAALGHHHGGQVGSYAGGAFNSTRDFLFRNRGAGIGETAPPSAQHGIFAASAGSLHGPPGISD 135

  Fly   108 AADSMLFSGFPAQAAELGSGFGQHPFHSHHHHHQMRMGM-ADAYAAGHPY--------NHHGNFP 163
            ....:||.|...|:....|..|      |..:.||.:|: .|.:....||        ..:|..|
Zfish   136 NPGHLLFPGLHDQSVSHTSPGG------HVVNSQMHLGLRGDIFGRPDPYRPVASPRTEPYGAAP 194

  Fly   164 TAAVHHPV-----VHHPSHHAMSAMHPAGAGAFLRYMRHQPASSASSVKQEMQCLWIDPDQPGLV 223
            ....:||:     ::.|:||        |.|||.|||| ||      :|||:.|.|||.:|  :.
Zfish   195 LHNYNHPINMNMGMNVPTHH--------GPGAFFRYMR-QP------IKQELSCKWIDENQ--MN 242

  Fly   224 PPGGRKTCNKVFHSMHEIVTHLTVEHVGGPECTTHACFWVGCSRNGRPFKAKYKLVNHIRVHTGE 288
            .|  :|||::.|.:|||:|||:::|||||||.:.|.|:|..|.|.|:.|||||||||||||||||
Zfish   243 RP--KKTCDRTFSTMHEMVTHVSMEHVGGPEQSNHVCYWEDCPREGKSFKAKYKLVNHIRVHTGE 305

  Fly   289 KPFACPHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKHSHVHTSDKPYNC 353
            |||.||.|||||:|||||||||||||||||||||||.:|||||||||||||||.|||||||||.|
Zfish   306 KPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFDGCDRRFANSSDRKKHMHVHTSDKPYIC 370

  Fly   354 RINGCDKSYTHPSSLRKHMKVH---GNVDEKSPSHGYDSEGEESSSSSIITGGAQTP---PSTRL 412
            ::  ||||||||||||||||||   |:....:.|.||:|    |:...:::...:.|   |::.:
Zfish   371 KV--CDKSYTHPSSLRKHMKVHESQGSESSPAASSGYES----STPPVLVSANTEDPTKTPTSAV 429

  Fly   413 DGSAGSSSGV 422
            ..|:..|.|:
Zfish   430 QNSSAHSDGL 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
opa	NP_001368991.1	zf_ZIC	206..253	CDD:436441	23/46 (50%)
		C2H2 Zn finger	265..285	CDD:275368	15/19 (79%)
		SFP1	<287..373	CDD:227516	74/85 (87%)
		C2H2 Zn finger	293..315	CDD:275368	19/21 (90%)
		C2H2 Zn finger	323..345	CDD:275368	18/21 (86%)
		C2H2 Zn finger	353..375	CDD:275368	17/21 (81%)
zic3	NP_001001950.1	zf_ZIC	225..270	CDD:436441	25/54 (46%)
		C2H2 Zn finger	282..302	CDD:275368	15/19 (79%)
		SFP1	<304..388	CDD:227516	74/85 (87%)
		C2H2 Zn finger	310..332	CDD:275368	19/21 (90%)
		C2H2 Zn finger	340..362	CDD:275368	18/21 (86%)
		C2H2 Zn finger	370..390	CDD:275368	17/21 (81%)