DRSC/TRiP Functional Genomics Resources

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Protein Alignment opa and Prdm9

DIOPT Version :9

Sequence 1:NP_001368991.1 Gene:opa / 40605 FlyBaseID:FBgn0003002 Length:688 Species:Drosophila melanogaster
Sequence 2:NP_001102373.2 Gene:Prdm9 / 365155 RGDID:1305247 Length:796 Species:Rattus norvegicus


Alignment Length:147 Identity:53/147 - (36%)
Similarity:70/147 - (47%) Gaps:15/147 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   229 KTCNKVFHSMHEIVTHLTVEHVGGPECTTHACFWVGCSRNGRPFKAKYKLVNHIRVHTGEKPFAC 293
            :.|.:.|....:::.|........|..         |...||.|..|..|:.|.|.||.|||:.|
  Rat   549 RECGRGFSQKSDLIKHQRTHTEEKPYI---------CRECGRGFTQKSDLIKHQRTHTEEKPYIC 604

  Fly   294 PHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKHSHVHTSDKPYNCRINGC 358
            ..  ||:.|.:..:|..|:||||||||:.|..  |.|.|...||..||...||.:|||.||  .|
  Rat   605 RE--CGRGFTQKSDLIKHQRTHTGEKPYICRE--CGRGFTQKSDLIKHQRTHTEEKPYICR--EC 663

  Fly   359 DKSYTHPSSLRKHMKVH 375
            .:.:|..|||.:|.:.|
  Rat   664 GRGFTQKSSLIRHQRTH 680

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
opaNP_001368991.1 zf_ZIC 206..253 CDD:408166 3/23 (13%)
C2H2 Zn finger 265..285 CDD:275368 8/19 (42%)
SFP1 <287..373 CDD:227516 38/85 (45%)
C2H2 Zn finger 293..315 CDD:275368 7/21 (33%)
C2H2 Zn finger 323..345 CDD:275368 8/21 (38%)
C2H2 Zn finger 353..375 CDD:275368 8/21 (38%)
Prdm9NP_001102373.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..23
KRAB_A-box 32..89 CDD:383038
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 149..172
SSXRD 175..205 CDD:370541
PR-SET_PRDM7_9 244..372 CDD:380970
S-adenosyl-L-methionine binding. /evidence=ECO:0000250|UniProtKB:Q96EQ9 260..262
Substrate binding. /evidence=ECO:0000250|UniProtKB:Q96EQ9 292..298
S-adenosyl-L-methionine binding. /evidence=ECO:0000250|UniProtKB:Q96EQ9 324..325
COG5048 402..748 CDD:227381 53/147 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 443..497
C2H2 Zn finger 521..540 CDD:275368
C2H2 Zn finger 548..568 CDD:275368 3/18 (17%)
C2H2 Zn finger 576..596 CDD:275368 8/19 (42%)
C2H2 Zn finger 604..624 CDD:275368 7/21 (33%)
C2H2 Zn finger 632..652 CDD:275368 8/21 (38%)
C2H2 Zn finger 660..680 CDD:275368 8/21 (38%)
C2H2 Zn finger 688..708 CDD:275368
C2H2 Zn finger 716..736 CDD:275368
C2H2 Zn finger 744..764 CDD:275368
C2H2 Zn finger 772..792 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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