Protein Alignment opa and Zxdc

DIOPT Version :10

• Sequence 1: NP_001368991.1
• Gene: opa / 40605
• FlyBaseID: FBgn0003002
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001418710.1
• Gene: Zxdc / 362399
• RGDID: 1561296
• Length: 878
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 146/666 - (21%)
• Similarity: 226/666 - (33%)
• Gaps: 178/666 - (26%)

  Fly    46 QQQQQQQQQQQQQQDQESAAATAAAYQNSGYGHFNSYASRDFLLGRREAEYGVAGSAGQASAAAD 110
            :|::.:........:|..|||..||...:...|     ::|.|:......:.:|.:...|:....
  Rat   110 EQEETEPDSGASPTEQVPAAAPGAALAGTVTIH-----NQDLLVRFDRGVFTLAAAPAPATQGLH 169

  Fly   111 SMLFSGF-PAQAAELGSGFGQHPFHSHHHHHQMRMGMADAYAAGHPYNHHGNFPTAAV-----HH 169
            .....|. |:.||                  ..|.|.. |.:||.| .:....|..|:     |.
  Rat   170 PATTPGLEPSSAA------------------ASRRGPV-AASAGSP-AYRCPEPQCALSFAKKHQ 214

  Fly   170 PVVHHPSHHAMSAMHP-----AGAG-AFLRYMRHQPASSASSVKQEMQCLWIDPDQPGLVPPGGR 228
            ..||..:|.::....|     .|.| ||         :::..:|:.:|.  .|..:|...|.||
  Rat   215 LKVHLLTHGSLQGRRPFKCPLDGCGWAF---------TTSYKLKRHLQS--HDKLRPFSCPVGG- 267

  Fly   229 KTCNKVFHSMHEIVTHLTVE--------HVGGPECTTHA-----------------CFWVGCSRN 268
              |.|.|.:::.:..|:...        .|......|||                 |.:.||.:.
  Rat   268 --CGKKFTTVYNLKAHMKGHEQESLFKCEVCAERFPTHAKLNSHQRSHFEPERPYKCDFPGCEKT 330

  Fly   269 GRPFKAKYKLVNHIRVHTGEKP-FACPHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRF 332
               |.....|.:|.|.|..|:. |:|..|||.|.:.::..||||.|:||||:||.|:.:.|...|
  Rat   331 ---FITVSALFSHNRAHFREQELFSCSFPGCNKQYDKACRLKIHLRSHTGERPFICDSDSCGWTF 392

  Fly   333 ANSSDRKKHSHVHTSDKPYNCRINGCDKSYTHPSSLRKHMKVHGNVDEKSPSHGYDSEGEESSSS 397
            .:.|...:|...|..|:.:.|.:.||.||:|.    .:|:|.|.
  Rat   393 TSMSKLLRHKRKHDDDRRFTCPVEGCGKSFTR----AEHLKGHS--------------------- 432

  Fly   398 SIITGGAQTPPSTRLDGSAGSSSGVSSLSGGSGIKSSPHSIKSEPNPMHSVHLGASSSGSSSTAS 462
              ||.....|....::|.....|..|||        ..||.|         ||....:..|....
  Rat   433 --ITHLGTKPFECPVEGCCARFSARSSL--------YIHSKK---------HLQDVGTPKSRCPV 478

  Fly   463 SSASHLL--QHQQHQHQQQQQQQQHQQQAQQQQQLTAHPSDPKSSPALQLMA--ASASAYLPPPL 523
            ||.:.|.  :|....|..:|..::.....|.:...:..||...|||....:.  ..|:.:...|
  Rat   479 SSCNRLFTSKHSMKAHMVRQHSRRQDLVPQLEAPSSLTPSSELSSPGQSELTNIDLAALFSDTP- 542

  Fly   524 GPPPSHHHHPHHHQAAPSPGAAAASASMLHHNHHLLYHPAAQHHPPSDWYHTTAPSGSAEAMNPL 588
                           |.|..:.|.|...|  |..:|            ....|:.|.|.....|.
  Rat   543 ---------------ANSSSSTAGSDEAL--NSGIL------------TIDVTSVSSSLGGNLPT 578

  Fly   589 NH--FGHHHHHHHLMHPGAATAYXEWENWWPEEAPPPAAQP--MATPTTI-AGGTGPAQGSVEES 648
            |:  .|.       |.|....|:        .:.||....|  :.||.|: ..|:..|..|...|
  Rat   579 NNNSLGP-------MDPLVLVAH--------SDMPPSLDSPLVLGTPATVLQPGSFSADDSQAMS 628

  Fly   649 ASSLDWICCQRLQNLA 664
            ..::..:....::||:
  Rat   629 TGAVGCLVALPMRNLS 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
opa	NP_001368991.1	zf_ZIC	206..253	CDD:436441	12/54 (22%)
		C2H2 Zn finger	265..285	CDD:275368	5/19 (26%)
		SFP1	<287..373	CDD:227516	32/86 (37%)
		C2H2 Zn finger	293..315	CDD:275368	10/21 (48%)
		C2H2 Zn finger	323..345	CDD:275368	5/21 (24%)
		C2H2 Zn finger	353..375	CDD:275368	8/21 (38%)
Zxdc	NP_001418710.1	COG5048	<198..385	CDD:227381	53/203 (26%)
		C2H2 Zn finger	200..222	CDD:275368	5/21 (24%)
		C2H2 Zn finger	233..255	CDD:275368	6/32 (19%)
		zf-C2H2_8	263..340	CDD:464935	16/82 (20%)
		C2H2 Zn finger	263..285	CDD:275368	7/24 (29%)
		C2H2 Zn finger	293..313	CDD:275368	4/19 (21%)
		C2H2 Zn finger	322..344	CDD:275368	7/24 (29%)
		C2H2 Zn finger	356..375	CDD:275368	9/18 (50%)
		C2H2 Zn finger	383..405	CDD:275368	5/21 (24%)
		zf-H2C2_2	398..424	CDD:463886	8/25 (32%)
		C2H2 Zn finger	413..435	CDD:275368	10/48 (21%)
		COG5048	414..>692	CDD:227381	64/320 (20%)
		C2H2 Zn finger	443..465	CDD:275368	8/38 (21%)