Protein Alignment opa and Glis2

DIOPT Version :10

• Sequence 1: NP_001368991.1
• Gene: opa / 40605
• FlyBaseID: FBgn0003002
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: XP_038941774.1
• Gene: Glis2 / 302946
• RGDID: 1309177
• Length: 522
• Species: Rattus norvegicus
• Alignment Length: 427
• Identity: 133/427 - (31%)
• Similarity: 188/427 - (44%)
• Gaps: 89/427 - (20%)

  Fly   163 PTAAVHHPVVH---HPSHHAMSAMHPAGAGAFLRYMRHQPASSASS------------VKQEMQC 212
            |||....|:.:   .||  :.....|.|:|..|    |.||||..:            :.:::.|
  Rat   112 PTAVDFQPLRYLDGVPS--SFQFFLPLGSGGAL----HLPASSFLTPPKDKCLSPELPLAKQLVC 170

  Fly   213 LWIDPDQPGLVPPGGRKTCNKVFHSMHEIVTHLTVEHVGGPECTTHACFWVGCSRNGRPFKA-KY 276
            .|              ..||::|..:.::|.|:...||...:...:.|.|.||:|:||.|.| :|
  Rat   171 RW--------------AKCNQLFELLQDLVDHVNDHHVKPEQDARYCCHWEGCARHGRGFNASRY 221

  Fly   277 KLVNHIRVHTGEKPFACPHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKH 341
            |::.|||.||.|||..|  |.|.|.|:|.||||||.|:||||||:.|.:|||::|::|||||.||
  Rat   222 KMLIHIRTHTNEKPHRC--PTCNKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKH 284

  Fly   342 SHVHTSDKPYNCRINGCDKSYTHPSSLRKHMKVHGNV-------------DEKSPSHGYDSEGEE 393
            :..|..||||.|::.||.|.||.|||||||:|.||:.             ..|.|....||....
  Rat   285 TRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPTPDSGSYV 349

  Fly   394 SSSSSIIT------GGAQTPP------------STRLDGSAGSSSGVSSLSGGSGIKSSPHSIKS 440
            |.:..||.      ||...|.            |....|:.|...|    ..|.|:..|...:..
  Rat   350 SGAQIIIPNPAALFGGPSLPGLPLPLAPGPLDLSALACGNGGGGGG----GMGPGLPGSVLPLNL 410

  Fly   441 EPNPMHSVHLGASSSGSS--STASSSASHLLQHQQHQHQQQQQ---QQQHQQQAQQQQQLTAHPS 500
            ..||:.....||...|..  |....||....:.::.:.....:   .:.|:...::.::..:.||
  Rat   411 AKNPLLPSPFGAGGLGLPVVSLLGGSAGSKAEGEKGRGSVPARVLGLEDHKTSLERTERSRSRPS 475

  Fly   501 DPKSSP-----ALQLMAASASAYLPPPLGP-----PP 527
             |...|     .|.|...:::|..|..|.|     ||
  Rat   476 -PDGLPLLPGTVLDLSTGNSAASSPEALTPGWVVIPP 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
opa	NP_001368991.1	zf_ZIC	206..253	CDD:436441	9/46 (20%)
		C2H2 Zn finger	265..285	CDD:275368	11/20 (55%)
		SFP1	<287..373	CDD:227516	52/85 (61%)
		C2H2 Zn finger	293..315	CDD:275368	13/21 (62%)
		C2H2 Zn finger	323..345	CDD:275368	12/21 (57%)
		C2H2 Zn finger	353..375	CDD:275368	14/21 (67%)
Glis2	XP_038941774.1	C2H2 Zn finger	213..230	CDD:275368	9/16 (56%)
		COG5048	234..>328	CDD:227381	54/95 (57%)
		C2H2 Zn finger	238..258	CDD:275368	13/21 (62%)
		C2H2 Zn finger	266..288	CDD:275368	12/21 (57%)
		C2H2 Zn finger	296..318	CDD:275368	14/21 (67%)