Protein Alignment opa and zic1

DIOPT Version :10

• Sequence 1: NP_001368991.1
• Gene: opa / 40605
• FlyBaseID: FBgn0003002
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_571008.1
• Gene: zic1 / 30096
• ZFINID: ZDB-GENE-000208-4
• Length: 442
• Species: Danio rerio
• Alignment Length: 444
• Identity: 210/444 - (47%)
• Similarity: 251/444 - (56%)
• Gaps: 106/444 - (23%)

  Fly    61 QESAAATAAAYQNSGYGH--------------FNSYASRDFLLGRR------EAEYGVAGSAGQA 105
            |.:.::.|..|..:..||              |||  :||||...|      .|::.:..||..:
Zfish    60 QTAFSSQAPGYAAAALGHHHHPTHVSSYSTAAFNS--TRDFLFRNRGFGDATSAQHSLFASAAGS 122

  Fly   106 -------SAAADSMLFSGFPAQAAELGSGFGQHPFHSHHHHHQMRMGMA-DAYAAGHPYNH---- 158
                   |.||..:||.|...|||...|        |:..:.|||:|.: |.|.....|.|
Zfish   123 FAGPHGHSDAAGHLLFPGLHEQAATHAS--------SNVVNSQMRLGFSGDMYGRAEQYGHVASP 179

  Fly   159 -HGNFPTAAVHHPVVHHPSHHAMSAMHPAGAGAFLRYMRHQPASSASSVKQEMQCLWIDPDQPGL 222
             ..::.:..:|.   :.|.:..|:|.|  |||||.|||| ||      :|||:.|.||:|:|  |
Zfish   180 RSEHYASTQLHG---YGPMNMNMAAHH--GAGAFFRYMR-QP------IKQELICKWIEPEQ--L 230

  Fly   223 VPPGGRKTCNKVFHSMHEIVTHLTVEHVGGPECTTHACFWVGCSRNGRPFKAKYKLVNHIRVHTG 287
            ..|  :|:|||.|.:|||:|||||||||||||.:.|.|||..|.|.|:|||||||||||||||||
Zfish   231 TNP--KKSCNKTFSTMHELVTHLTVEHVGGPEQSNHICFWEECGREGKPFKAKYKLVNHIRVHTG 293

  Fly   288 EKPFACPHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKHSHVHTSDKPYN 352
            ||||.||.|||||||||||||||||||||||||||||.||||||||||||||||.|||||||||.
Zfish   294 EKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYL 358

  Fly   353 CRINGCDKSYTHPSSLRKHMKVHGNVDEKSPSHGYDSEGEESSSSSIITGGAQTPPSTRLDGSAG 417
            |::  ||||||||||||||||||                 ||||.     |:|..|:
Zfish   359 CKM--CDKSYTHPSSLRKHMKVH-----------------ESSSQ-----GSQPSPA-------- 391

  Fly   418 SSSGVSSLSGGSGIKSSPHSIKSEPNPMHSVHLGASSSGSSSTASSSASHLLQH 471
            :|||..|        |:|.:|.| |:..:      .||.|.|.|||:..|...|
Zfish   392 ASSGYES--------STPPTIVS-PSTEN------QSSSSISPASSTVHHTSSH 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
opa	NP_001368991.1	zf_ZIC	206..253	CDD:436441	28/46 (61%)
		C2H2 Zn finger	265..285	CDD:275368	16/19 (84%)
		SFP1	<287..373	CDD:227516	76/85 (89%)
		C2H2 Zn finger	293..315	CDD:275368	20/21 (95%)
		C2H2 Zn finger	323..345	CDD:275368	19/21 (90%)
		C2H2 Zn finger	353..375	CDD:275368	17/21 (81%)
zic1	NP_571008.1	zf_ZIC	214..259	CDD:436441	30/54 (56%)
		C2H2 Zn finger	269..291	CDD:275368	16/21 (76%)
		SFP1	<293..377	CDD:227516	76/85 (89%)
		C2H2 Zn finger	299..321	CDD:275368	20/21 (95%)
		C2H2 Zn finger	329..351	CDD:275368	19/21 (90%)
		C2H2 Zn finger	359..379	CDD:275368	17/21 (81%)