DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment opa and iec1

DIOPT Version :9

Sequence 1:	NP_001368991.1	Gene:	opa / 40605	FlyBaseID:	FBgn0003002	Length:	688	Species:	Drosophila melanogaster
Sequence 2:	NP_594663.1	Gene:	iec1 / 2542854	PomBaseID:	SPAC144.02	Length:	249	Species:	Schizosaccharomyces pombe

Alignment Length:	187	Identity:	50/187 - (26%)
Similarity:	77/187 - (41%)	Gaps:	42/187 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 KQEMQCLWIDPDQPGLVPPGGRKTCNKVFHSMH-------EIVTHLT--VEHVGG--PECTTHAC 260
            :.|..|.|...:|..|       |.:.:.|.:|       .:::::.  ::|:|.  |:.|   |
pombe    21 ESETICHWQSCEQDLL-------TLDNLVHHIHNGTTSNLRLISNINSILDHIGNRRPKYT---C 75

  Fly   261 FWVGCSRNGRPFKAKYKLVNHIRVHTGEKPFACPHPGCGKVFARSENLKIHKRTHTGEKPFKCEH 325
            .|..|.|.|....:::.||.|:|.|||||||.|..|.|.:.|.||:.|..|.||         .|
pombe    76 EWDDCPRKGMVQTSRFALVAHLRSHTGEKPFICSVPECDRSFTRSDALAKHMRT---------VH 131

  Fly   326 EGCDRRFANSSDRKKHSHVHTSDKPYNCRINGCDKSYTHPSSLRKHMKVH--GNVDE 380
            |....|   .||....:|........|..:....::       |...::|  ||.:|
pombe   132 EADTLR---PSDPIPKAHPMHPQNVANAMVQSAREA-------RAQQQMHGVGNTNE 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
opa	NP_001368991.1	zf_ZIC	206..253	CDD:408166	10/56 (18%)
		C2H2 Zn finger	265..285	CDD:275368	7/19 (37%)
		SFP1	<287..373	CDD:227516	23/85 (27%)
		C2H2 Zn finger	293..315	CDD:275368	9/21 (43%)
		C2H2 Zn finger	323..345	CDD:275368	6/21 (29%)
		C2H2 Zn finger	353..375	CDD:275368	1/21 (5%)
iec1	NP_594663.1	COG5048	1..>249	CDD:227381	50/187 (27%)
		zf-H2C2_2	92..119	CDD:290200	15/26 (58%)
		C2H2 Zn finger	108..129	CDD:275368	8/20 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000467
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X217
TreeFam	0	0.000	Not matched by this tool.
	2	2.000