Protein Alignment opa and Zic1

DIOPT Version :10

• Sequence 1: NP_001368991.1
• Gene: opa / 40605
• FlyBaseID: FBgn0003002
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_033599.2
• Gene: Zic1 / 22771
• MGIID: 106683
• Length: 447
• Species: Mus musculus
• Alignment Length: 467
• Identity: 217/467 - (46%)
• Similarity: 253/467 - (54%)
• Gaps: 104/467 - (22%)

  Fly     3 MNAF-IEPAQHHLASYGLRMSPNTTASNSNAQQQQQQQLEMTQQQQQQQQQQQQQQQQDQESAAA 66
            |.|| :.|:.|.|||.|      .||..|.|                             ...||
Mouse    44 MGAFKLNPSSHELASAG------QTAFTSQA-----------------------------PGYAA 73

  Fly    67 TAAAYQNSGYGHFNSYAS------RDFLLGRREAEYGVAGSAGQASA------------------ 107
            .||...:...||..||:|      ||||...|    |...:|..|||
Mouse    74 AAALGHHHHPGHVGSYSSAAFNSTRDFLFRNR----GFGDAAAAASAQHSLFAASAGGFGGPHGH 134

  Fly   108 --AADSMLFSGFPAQAAELGSGFGQHPFHSHHH--HHQMRMGMA-DAYAAGHPYNHHGNFPTAAV 167
              ||..:||||...|||.          |:..:  :.|||:|.: |.|.....|   |...:...
Mouse   135 TDAAGHLLFSGLHEQAAG----------HASPNVVNGQMRLGFSGDMYPRPEQY---GQVTSPRS 186

  Fly   168 HH---PVVH--HPSHHAMSAMHPAGAGAFLRYMRHQPASSASSVKQEMQCLWIDPDQPGLVPPGG 227
            .|   |.:|  .|.:..|:|.|  |||||.|||| ||      :|||:.|.||:|:|  |..|
Mouse   187 EHYAAPQLHGYGPMNVNMAAHH--GAGAFFRYMR-QP------IKQELICKWIEPEQ--LANP-- 238

  Fly   228 RKTCNKVFHSMHEIVTHLTVEHVGGPECTTHACFWVGCSRNGRPFKAKYKLVNHIRVHTGEKPFA 292
            :|:|||.|.:|||:|||:|||||||||.:.|.|||..|.|.|:|||||||||||||||||||||.
Mouse   239 KKSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFP 303

  Fly   293 CPHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKHSHVHTSDKPYNCRING 357
            ||.|||||||||||||||||||||||||||||.||||||||||||||||.|||||||||.|::
Mouse   304 CPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKM-- 366

  Fly   358 CDKSYTHPSSLRKHMKVHGNVDEKSPSHGYDSEGEESSSSSIITGGAQTPPSTRLDGSAGSSSGV 422
            ||||||||||||||||||.:..:.|......|.|.|||:...|.......|:|  ...:.|||.|
Mouse   367 CDKSYTHPSSLRKHMKVHESSSQGSQPSPAASSGYESSTPPTIVSPTTDNPTT--SSMSPSSSAV 429

  Fly   423 SSLSGGSGIKSS 434
            ...:|.|.:.|:
Mouse   430 HHTAGHSALSSN 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
opa	NP_001368991.1	zf_ZIC	206..253	CDD:436441	27/46 (59%)
		C2H2 Zn finger	265..285	CDD:275368	16/19 (84%)
		SFP1	<287..373	CDD:227516	76/85 (89%)
		C2H2 Zn finger	293..315	CDD:275368	20/21 (95%)
		C2H2 Zn finger	323..345	CDD:275368	19/21 (90%)
		C2H2 Zn finger	353..375	CDD:275368	17/21 (81%)
Zic1	NP_033599.2	zf_ZIC	219..264	CDD:436441	29/54 (54%)
		C2H2 Zn finger	276..296	CDD:275368	16/19 (84%)
		SFP1	<298..382	CDD:227516	76/85 (89%)
		C2H2 Zn finger	304..326	CDD:275368	20/21 (95%)
		C2H2 Zn finger	334..356	CDD:275368	19/21 (90%)
		C2H2 Zn finger	364..384	CDD:275368	17/21 (81%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	375..434		23/60 (38%)