Protein Alignment opa and ref-2

DIOPT Version :10

• Sequence 1: NP_001368991.1
• Gene: opa / 40605
• FlyBaseID: FBgn0003002
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001024478.1
• Gene: ref-2 / 183539
• WormBaseID: WBGene00004335
• Length: 315
• Species: Caenorhabditis elegans
• Alignment Length: 350
• Identity: 133/350 - (38%)
• Similarity: 172/350 - (49%)
• Gaps: 87/350 - (24%)

  Fly   110 DSMLFSGFPAQAAELGSGFGQHPFHSHHHHHQMRMGMADAYAAGHPYNH-HGNFPTAAVHHPVVH 173
            |.|:.|.:..|:.  |....|.|               :..|:..||:. |...|:..::...|.
 Worm    11 DKMMHSDYYTQSQ--GPTVEQQP---------------EWQASVQPYSDPHAYSPSFYMNMSQVP 58

  Fly   174 HPSHHAMSAMHPAGAGAFLRYMRHQPASSAS-SVKQEMQCLWIDPDQPGLVPPGGRKTCNKVFHS 237
            |        ..||....|:     .|.:..| ...:::||||....|          .|..|..:
 Worm    59 H--------FLPAQVDPFI-----YPNTLGSYGGDKQVQCLWETNGQ----------VCMHVCQN 100

  Fly   238 MHEIVTHLTVEHVGGPECTTH----ACFWVGCSRNGRPFKAKYKLVNHIRVHTGEKPFACPHPGC 298
            ..|:.||::..|:      ||    .|.|.||.|..:.||||||||||:||||||:||.|  ..|
 Worm   101 SGELSTHISSNHI------THDSKFVCLWKGCDREFKMFKAKYKLVNHMRVHTGERPFLC--DVC 157

  Fly   299 GKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKHSHVHTSDKPYNCRINGCDKSYT 363
            .||||||||||||||.|:|||||:|.|.||.:.||||||||||.|||:|.|||:|....|.|:||
 Worm   158 NKVFARSENLKIHKRIHSGEKPFQCTHNGCTKLFANSSDRKKHMHVHSSHKPYSCMYPDCGKTYT 222

  Fly   364 HPSSLRKHMKVHGNVDEK----SPSHGYDSEGEESSSSSIITGGAQTPPSTRLDGSAGSSSGVSS 424
            ||||||||.|||.|  ||    ||.|   .|..:|.::||.|      |:|
 Worm   223 HPSSLRKHTKVHEN--EKKSQLSPEH---DESSDSGNASIGT------PTT-------------- 262

  Fly   425 LSGGSGIKSSPHSIKSEPNPMHSVH 449
               ...:..||.:||.:.: :|::|
 Worm   263 ---DESLTFSPENIKRDQH-LHTMH 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
opa	NP_001368991.1	zf_ZIC	206..253	CDD:436441	11/46 (24%)
		C2H2 Zn finger	265..285	CDD:275368	13/19 (68%)
		SFP1	<287..373	CDD:227516	60/85 (71%)
		C2H2 Zn finger	293..315	CDD:275368	16/21 (76%)
		C2H2 Zn finger	323..345	CDD:275368	15/21 (71%)
		C2H2 Zn finger	353..375	CDD:275368	14/21 (67%)
ref-2	NP_001024478.1	COG5048	150..>227	CDD:227381	53/78 (68%)
		C2H2 Zn finger	154..174	CDD:275368	16/21 (76%)
		C2H2 Zn finger	182..204	CDD:275368	15/21 (71%)
		C2H2 Zn finger	212..234	CDD:275368	14/21 (67%)