Protein Alignment opa and tra-1

DIOPT Version :10

• Sequence 1: NP_001368991.1
• Gene: opa / 40605
• FlyBaseID: FBgn0003002
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001022880.2
• Gene: tra-1 / 176548
• WormBaseID: WBGene00006604
• Length: 1110
• Species: Caenorhabditis elegans
• Alignment Length: 587
• Identity: 176/587 - (29%)
• Similarity: 236/587 - (40%)
• Gaps: 156/587 - (26%)

  Fly     6 FIE---PAQHHLASYGLRMSPNTTASNSNAQQQQQQQLEMTQQQQQQQQQQQQQQQQDQESAAAT 67
            ||:   |..|...|..|::||  .|..|.|||....|:..|.|                   ||.
 Worm    73 FIQSSVPPSHQTLSNPLQLSP--PAEASVAQQSGASQVFPTFQ-------------------AAL 116

  Fly    68 AAAYQNSGYGHFNSYASRDFLLGRREAEYGVAGSAGQASAAADSML-FSGFPAQAAELGS----G 127
            .              ||.|.||     :.....|:..:||:..|:: ...|..|.|..||    .
 Worm   117 G--------------ASSDELL-----QPNATSSSTSSSASTSSIVPVVKFTNQTAPNGSTVATS 162

  Fly   128 FGQHPFHSHHHHHQMRMGMADAYAAGHPYNHHGNFPTAAVHHPVVHHPSHHAMSAMHPAGAGAFL 192
            .||:          :|:.: :....|.|                                .|.|.
 Worm   163 VGQN----------VRLTI-NGKRVGRP--------------------------------PGTFK 184

  Fly   193 RYMRHQPASSASSVKQEMQ------CLWIDPDQPGLVPPGGRKTCNKVFHSMHEIVTHLTVEHVG 251
            |...:...||.|....:|.      |.|              |:||..|.::..:|.|:...||.
 Worm   185 RPQNNAANSSNSGNDSDMMGDHDLTCRW--------------KSCNSSFQTLKALVDHVQESHVQ 235

  Fly   252 GPECTTHA--CFWVGCSRNGRPFKAKYKLVNHIRVHTGEKPFACPHPGCGKVFARSENLKIHKRT 314
            ..|...||  |.|.||.|| ..|||.|.|:.|:|.||||||..|.:|||||.::|.||||.|:||
 Worm   236 STEQEHHAWRCEWEGCDRN-ETFKALYMLIVHVRRHTGEKPNKCEYPGCGKEYSRLENLKTHRRT 299

  Fly   315 HTGEKPFKCEHEGCDRRFANSSDRKKH-SHVHTSDKPYNCRINGCDKSYTHPSSLRKHMK-VHGN 377
            ||||||:|||...|::.|:|:|||.|| :..|::.|||:|:|..|.||||.|||||||:| |||
 Worm   300 HTGEKPYKCEFADCEKAFSNASDRAKHQNRTHSNLKPYSCQIPQCTKSYTDPSSLRKHIKAVHG- 363

  Fly   378 VDEKSPSHGYDSEGEESSSSSIITGGAQTPPSTRLDGSAGSSSGVSSLSGGSGIKSSPHS----- 437
                      |.|.|::..|.......:..|..||....|:.|.....:..||.....||
 Worm   364 ----------DDEYEKAKKSRPANYSNRRRPDHRLAPPTGAMSHPYLATPNSGASVVAHSSVHQQ 418

  Fly   438 -------IKSEPNPMHSVHLGASS---------SGSSSTASSSASHLLQHQQ---HQHQQQQQQQ 483
                   .:...|...:..|.|::         :.:::.|.:.|.|..|.|.   |..||.|.|.
 Worm   419 NFINMALAQHHHNAQRAQQLMAATGNVMPMMDPASAAAAAQAQAHHQAQAQMLQTHMMQQAQIQA 483

  Fly   484 QHQQQAQQQQQ--LTAHPSDPKSSPALQLMAASASAYLPP--PLGPPPSHHHHPHHHQAAPSPGA 544
            ..|.|||.|.|  :.||... ::...||.....|.:.|.|  ||.||....:.....|..|:|.:
 Worm   484 AAQMQAQVQHQAAMQAHAMQ-QAQMVLQNNLLGAQSLLSPFSPLLPPSRAPNVMAMLQTPPTPTS 547

  Fly   545 AA 546
            .|
 Worm   548 VA 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
opa	NP_001368991.1	zf_ZIC	206..253	CDD:436441	11/52 (21%)
		C2H2 Zn finger	265..285	CDD:275368	10/19 (53%)
		SFP1	<287..373	CDD:227516	53/86 (62%)
		C2H2 Zn finger	293..315	CDD:275368	13/21 (62%)
		C2H2 Zn finger	323..345	CDD:275368	10/22 (45%)
		C2H2 Zn finger	353..375	CDD:275368	15/22 (68%)
tra-1	NP_001022880.2	COG5048	<177..358	CDD:227381	89/227 (39%)
		C2H2 Zn finger	246..270	CDD:275368	13/24 (54%)
		SFP1	<272..362	CDD:227516	54/89 (61%)
		C2H2 Zn finger	278..300	CDD:275368	13/21 (62%)
		zf-H2C2_2	292..319	CDD:463886	17/26 (65%)
		C2H2 Zn finger	308..331	CDD:275368	10/22 (45%)
		C2H2 Zn finger	339..362	CDD:275368	15/22 (68%)