Protein Alignment BBS5 and BBS5

DIOPT Version :10

• Sequence 1: NP_649499.1
• Gene: BBS5 / 40600
• FlyBaseID: FBgn0037280
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_689597.1
• Gene: BBS5 / 129880
• HGNCID: 970
• Length: 341
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 166/359 - (46%)
• Similarity: 235/359 - (65%)
• Gaps: 21/359 - (5%)

  Fly    15 VLQLLWEDKEVKFDVPQLHKNLRSGERVLDYIYHIEDSKGNPGDTGRLMVTNLRIIWHSLVHKKY 79
            ||..||||::|:||:.......|.||.::|.:..|||:|||.||.|||:||||||:||||...:.
Human     3 VLDALWEDRDVRFDLSAQQMKTRPGEVLIDCLDSIEDTKGNNGDRGRLLVTNLRILWHSLALSRV 67

  Fly    80 NLSIGYARIGNTNTRVVHMHSKARIASQALYILAVSNETRFEFLFTDVSGETSRRDQPIFASVFD 144
            |:|:||..|.|..||..  :||.|..::|||||...|.|||||:||::...:.|    :|.||..
Human    68 NVSVGYNCILNITTRTA--NSKLRGQTEALYILTKCNSTRFEFIFTNLVPGSPR----LFTSVMA 126

  Fly   145 VYHLYQRTYLYRDLKLRGAIVQAGQLVILPDEEVFSHVQGVWNLSSDQGNLGSFVVTNIRLVWFA 209
            |:..|:.:.:|||.|||.|::|..||.:||.|.|:..:.|||||||||||||:|.:||:|:||.|
Human   127 VHRAYETSKMYRDFKLRSALIQNKQLRLLPQEHVYDKINGVWNLSSDQGNLGTFFITNVRIVWHA 191

  Fly   210 DANETFNISLPYLQIESLRVRESKYGPALVIQTAETGGGYVLGFRVDPAERLNELFKELSSLHTV 274
            :.|::||:|:|||||.|:::|:||:|.||||::::..|||||||::||.|:|.|..||::|||.|
Human   192 NMNDSFNVSIPYLQIRSIKIRDSKFGLALVIESSQQSGGYVLGFKIDPVEKLQESVKEINSLHKV 256

  Fly   275 YGEHPNFGIQYNANDARRRLEAASEEAAQASQIKVDNFEELDERQEREINTKLNSYLAEGCLGKV 339
            |...|.||:.|...:..:.|||.:.|..| ..:::|:....|         ...:|.|:|
Human   257 YSASPIFGVDYEMEEKPQPLEALTVEQIQ-DDVEIDSDGHTD---------AFVAYFADG----- 306

  Fly   340 PSQGERAPVYCKELGFAMEPIGDGYKLQDLWNVM 373
            ..|.:|.||:.:|||.|:|.:.||:.||.||.||
Human   307 NKQQDREPVFSEELGLAIEKLKDGFTLQGLWEVM 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BBS5	NP_649499.1	BBL5	19..372	CDD:462136	162/352 (46%)
BBS5	NP_689597.1	BBL5	7..339	CDD:462136	151/331 (46%)