DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1129 and PSA1

DIOPT Version :9

Sequence 1:	NP_001189177.2	Gene:	CG1129 / 40599	FlyBaseID:	FBgn0037279	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_010228.1	Gene:	PSA1 / 851504	SGDID:	S000002213	Length:	361	Species:	Saccharomyces cerevisiae

Alignment Length:	360	Identity:	221/360 - (61%)
Similarity:	282/360 - (78%)	Gaps:	2/360 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RALILVGGYGTRLRPLTLSTPKPLVEFANKPILLHQLEALVDAGCRQVILAVSYRAEQMEKELKV 76
            :.||||||||||||||||:.|||||||.|:|::|||:|||.:||...::|||:||.|.|.:.||.
Yeast     2 KGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIVLAVNYRPEVMVETLKK 66

  Fly    77 EAKKLGVELIFSHETEPLGTAGPLALAKTILAASSEPFFVLNSDVICDFPFKQLVQFHCNHGKEG 141
            ..|:.||.:.||.|||||||||||.||:.:|...:.|||||||||||::|||:|..||..||.:|
Yeast    67 YEKEYGVNITFSVETEPLGTAGPLKLAEDVLKKDNSPFFVLNSDVICEYPFKELADFHKAHGGKG 131

  Fly   142 TIVVTKVEEPSKYGVVLYD--ENGCIKNFIEKPQEFVSNKINAGIYIFNPSVLDRIEVKPTSIEK 204
            |||.|||:|||||||:::|  ....|..|:|||:|||.|:||||:||.||.|:|.||:|||||||
Yeast   132 TIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPKEFVGNRINAGLYILNPEVIDLIEMKPTSIEK 196

  Fly   205 EVFPEMTQQQELYAMDLTGFWMDIGQPKDFLTGMCLYLSSLRQKQSPKLYTGPGVVGNVLVDPTA 269
            |.||.:.::::||:.||.|||||:|||||||:|..|||:||.::|..||.||..:|||.|:||||
Yeast   197 ETFPILVEEKQLYSFDLEGFWMDVGQPKDFLSGTVLYLNSLAKRQPKKLATGANIVGNALIDPTA 261

  Fly   270 KIGEGCRIGPNVTIGPDVVIEDGVCIKRSTILKGAIVRSHSWLDSCIVGWRSTVGRWVRIEGITV 334
            ||....:|||:|.|||:|.|.|||.|.||.:|..:.:::||.:.|.||||.||||:|.|:||:||
Yeast   262 KISSTAKIGPDVVIGPNVTIGDGVRITRSVVLCNSTIKNHSLVKSTIVGWNSTVGQWCRLEGVTV 326

  Fly   335 LGEDVIVKDELYINGGQVLPHKSIAASVPEPQIIM 369
            ||:||.||||:|||||:|||||||:.:||:..|||
Yeast   327 LGDDVEVKDEIYINGGKVLPHKSISDNVPKEAIIM 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1129	NP_001189177.2	GCD1	12..361	CDD:224129	216/350 (62%)
		M1P_guanylylT_B_like_N	12..242	CDD:133047	144/231 (62%)
		LbetaH	264..343	CDD:294107	45/78 (58%)
PSA1	NP_010228.1	M1P_guanylylT_B_like_N	1..234	CDD:133047	144/231 (62%)
PSA1	NP_010228.1	LbetaH	256..335	CDD:412191	45/78 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343018
Domainoid	1	1.000	302	1.000	Domainoid score	I219
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5578
Inparanoid	1	1.050	458	1.000	Inparanoid score	I238
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61084
OrthoFinder	1	1.000	-	-		FOG0000664
OrthoInspector	1	1.000	-	-		oto99016
orthoMCL	1	0.900	-	-		OOG6_100460
Panther	1	1.100	-	-	LDO	PTHR22572
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R739
SonicParanoid	1	1.000	-	-		X1646
TreeFam	1	0.960	-	-
	15	14.790