DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1129 and Gmppa

DIOPT Version :9

Sequence 1:	NP_001189177.2	Gene:	CG1129 / 40599	FlyBaseID:	FBgn0037279	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_006245329.1	Gene:	Gmppa / 501167	RGDID:	1560644	Length:	425	Species:	Rattus norvegicus

Alignment Length:	440	Identity:	136/440 - (30%)
Similarity:	200/440 - (45%)	Gaps:	99/440 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RALILVGG--YGTRLRPLTLSTPKPLVEFANKPILLHQLEALVDA-GCRQVILAVSYRA-EQMEK 72
            :|:||:||  .|||.|||:...||||...|..|::.|.:||.... |.::::|...|:. |.:.:
  Rat     3 KAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLIGFYQPDEALTQ 67

  Fly    73 ELKVEAKKLGVELIFSHETEPLGTAGPL-ALAKTILAASSEPFFVLNSDVICDFPFKQLVQFH-- 134
            .|:...::..:.:.:..|..||||.|.| .....|||.:.|.|||||:||..|||...::..|
  Rat    68 FLEAAQQEFNLPVRYLQEFTPLGTGGGLYHFRDQILAGAPEAFFVLNADVCSDFPLSAMLDAHRL 132

  Fly   135 -----------------CNHGKEGTIVVTKVEEPSKYGVVLYDENGCIKNFIEKPQEFVSNKINA 182
                             .|:|       ..||.|..:.|:         :::|||..|:|:.||.
  Rat   133 QRHPFLLLGTTANRTQSLNYG-------CIVENPQTHEVL---------HYVEKPSTFISDIINC 181

  Fly   183 GIYIFNPSVLDRI------------------EVKPTS--------IEKEVFPEMTQQQELYAMDL 221
            |||:|:|..|..:                  |..|.|        :|::||..:..|.::|....
  Rat   182 GIYLFSPEALKPLRDVFQRNQQDGQLCLALGEESPGSWPGAGTIRLEQDVFSALAGQGQIYVHLT 246

  Fly   222 TGFWMDIGQPKDFLTGMCLYLSSLRQKQSPKL--YT--GPGVVGNVLVDPTAKIGEGCRIGPNVT 282
            .|.|..|......|....|||...:.....:|  :|  ||.:.|||.:.||||:.....:||||:
  Rat   247 DGIWSQIKSAGSALYASRLYLGRYQITHPERLARHTAGGPRIRGNVYIHPTAKVAPSAVLGPNVS 311

  Fly   283 IGPDVVIEDGVCIKRSTILKGAIVRSHSWLDSCIVGWRSTVGRWVRIEG---------------- 331
            ||..|.|.:||.::.|.:|.||.::.|:.:...||||.||||||.|:||
  Rat   312 IGKGVTIGEGVRLRESIVLHGATLQEHTCVLHSIVGWGSTVGRWARVEGTPNDPNPNDPRARMDS 376

  Fly   332 ------------ITVLGEDVIVKDELYINGGQVLPHKSIAASVPEPQIIM 369
                        ||:||..|.:..|:.|....|||||.::.|... |||:
  Rat   377 ESLFKDGKLLPAITILGCRVRIPAEVLILNSIVLPHKELSRSFTN-QIIL 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1129	NP_001189177.2	GCD1	12..361	CDD:224129	132/430 (31%)
		M1P_guanylylT_B_like_N	12..242	CDD:133047	79/279 (28%)
		LbetaH	264..343	CDD:294107	37/106 (35%)
Gmppa	XP_006245329.1	M1P_guanylylT_A_like_N	4..266	CDD:133050	78/277 (28%)
Gmppa	XP_006245329.1	LbetaH	294..360	CDD:412191	30/65 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D336231at33208
OrthoFinder	1	1.000	-	-		FOG0000664
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820