Protein Alignment Gmppb and eif2b3

DIOPT Version :10

• Sequence 1: NP_649498.1
• Gene: Gmppb / 40599
• FlyBaseID: FBgn0037279
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_957368.1
• Gene: eif2b3 / 394049
• ZFINID: ZDB-GENE-040426-1039
• Length: 453
• Species: Danio rerio
• Alignment Length: 444
• Identity: 100/444 - (22%)
• Similarity: 178/444 - (40%)
• Gaps: 113/444 - (25%)

  Fly    12 RALILVGGYGTRLRPLTLSTPKPLVEFANKPILLHQLEALVDAGCRQVILAVSYRAEQMEKELKV 76
            :|:::..|.|:|:..||.:|||||:...|||::.:.|..|...|..:||:..:   ::::|.|..
Zfish     4 QAVLMAAGGGSRMMDLTYNTPKPLLPVGNKPLIWYPLNLLERVGFEEVIVITT---KEVQKALST 65

  Fly    77 EAK-----KLGVELIFSHETEPLGTAGPLALAKTILAASSEPFFVLNSDVICDFPFKQLVQFHCN 136
            :.:     |:.::::...|...:|||..|   :.|.........||:.|:|.|....::|.....
Zfish    66 DQRLKTDVKMKLDVVCIQEEADMGTADAL---RHIQQKIKTDILVLSCDLITDVALHEVVDLFRA 127

  Fly   137 HGKEGTIVVTKVEE-----PSKYG---------VVLYD---------------ENGCI--KNFIE 170
            |....:::::||.|     |.:.|         .|..|               |.|.:  |:.:.
Zfish   128 HNATLSMLMSKVHEFTETVPGQKGKKKAGEQRDFVGVDVTGKRLLFMANEADLEEGLVLRKSIMR 192

  Fly   171 K-PQEFV-SNKINAGIYIFNPSVLDRI--EVKPTSIEKEVFPEMT-------------------- 211
            | |:.|: :..::|.:|....||:|.:  ....|||..|:.|.:.
Zfish   193 KHPRMFIKTGLLDAHLYCLKRSVVDFLVHNKSVTSIRGELVPYLVRKQFSKSLNSQHVTEDSEKN 257

  Fly   212 -QQQELYA-MDL---------------TGFWMDI----------GQPKDFL----TGMCLYLSSL 245
             :|||.:. |||               ...|.|.          |:.:.::    .|||..:::|
Zfish   258 QKQQEAHINMDLLSTSKDEALLQLARERSCWNDHRGDMSEAYHGGKIRCYVHIMEDGMCYRVNTL 322

  Fly   246 -----RQKQSPKLYTGPGVVGNVLVDPTAKIGEGCRIGPNVTIGPDVVIEDGVCIKRSTILKGAI 305
                 ..:..|||:..|.      :.|||.:.|...:|.:..|||...|.|...||||.:....:
Zfish   323 AAYIEANRVVPKLFEEPP------IHPTAVVSERSLVGSDSIIGPSCQISDKTSIKRSNVGTSTV 381

  Fly   306 VRSHSWLDSCIVGWRSTVGRWVRIEGI-----TVLGEDVIVKDELYINGGQVLP 354
            ::....:.:.|:....|:.....|:|.     .|:|....:|..|..:|.:|.|
Zfish   382 IKEKVKITNSIIMNGVTIEEGCNIQGSVICSHAVIGRGADIKYCLVGSGQRVDP 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmppb	NP_649498.1	M1P_guanylylT_B_like_N	12..242	CDD:133047	70/320 (22%)
		LbetaH	264..343	CDD:469633	20/83 (24%)
eif2b3	NP_957368.1	eIF-2B_gamma_N	3..216	CDD:133041	51/217 (24%)
		LbH_eIF2B_gamma_C	358..438	CDD:100057	20/78 (26%)