DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1129 and Gmppb

DIOPT Version :9

Sequence 1:	NP_001189177.2	Gene:	CG1129 / 40599	FlyBaseID:	FBgn0037279	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001344611.1	Gene:	Gmppb / 331026	MGIID:	2660880	Length:	360	Species:	Mus musculus

Alignment Length:	359	Identity:	252/359 - (70%)
Similarity:	310/359 - (86%)	Gaps:	1/359 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RALILVGGYGTRLRPLTLSTPKPLVEFANKPILLHQLEALVDAGCRQVILAVSYRAEQMEKELKV 76
            :||||||||||||||||||||||||:|.||||||||:|||..||...|||||||.::.:|||:|.
Mouse     2 KALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQMLEKEMKA 66

  Fly    77 EAKKLGVELIFSHETEPLGTAGPLALAKTILAASSEPFFVLNSDVICDFPFKQLVQFHCNHGKEG 141
            :.::||:.:..|||.||||||||||||:.:|:.:::|||||||||||||||:.:||||.:||:||
Mouse    67 QEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQAMVQFHRHHGQEG 131

  Fly   142 TIVVTKVEEPSKYGVVLYD-ENGCIKNFIEKPQEFVSNKINAGIYIFNPSVLDRIEVKPTSIEKE 205
            :|:|||||||||||||:.: :.|.|..|:||||.|||||||||:||.:|:||.||::||||||||
Mouse   132 SILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILSPAVLQRIQLKPTSIEKE 196

  Fly   206 VFPEMTQQQELYAMDLTGFWMDIGQPKDFLTGMCLYLSSLRQKQSPKLYTGPGVVGNVLVDPTAK 270
            :||.|.::.:||||:|.||||||||||||||||||:|.|||||...:||:|||:||||||||:|:
Mouse   197 IFPVMAKEGQLYAMELQGFWMDIGQPKDFLTGMCLFLQSLRQKHPERLYSGPGIVGNVLVDPSAR 261

  Fly   271 IGEGCRIGPNVTIGPDVVIEDGVCIKRSTILKGAIVRSHSWLDSCIVGWRSTVGRWVRIEGITVL 335
            ||:.|.|||||::||.||:||||||:|.|:|:.|.:||||||:|||||||..||:|||:|.:|||
Mouse   262 IGQNCSIGPNVSLGPGVVVEDGVCIRRCTVLRDAHIRSHSWLESCIVGWRCRVGQWVRMENVTVL 326

  Fly   336 GEDVIVKDELYINGGQVLPHKSIAASVPEPQIIM 369
            ||||||.||||:||..|||||||..|||||:|||
Mouse   327 GEDVIVNDELYLNGASVLPHKSIGESVPEPRIIM 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1129	NP_001189177.2	GCD1	12..361	CDD:224129	244/349 (70%)
		M1P_guanylylT_B_like_N	12..242	CDD:133047	161/230 (70%)
		LbetaH	264..343	CDD:294107	55/78 (71%)
Gmppb	NP_001344611.1	M1P_guanylylT_B_like_N	1..233	CDD:133047	161/230 (70%)
Gmppb	NP_001344611.1	LbetaH	255..334	CDD:381831	55/78 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834542
Domainoid	1	1.000	329	1.000	Domainoid score	I1161
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5578
Inparanoid	1	1.050	535	1.000	Inparanoid score	I1184
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61084
OrthoDB	1	1.010	-	-		D336231at33208
OrthoFinder	1	1.000	-	-		FOG0000664
OrthoInspector	1	1.000	-	-		oto92066
orthoMCL	1	0.900	-	-		OOG6_100460
Panther	1	1.100	-	-	LDO	PTHR22572
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R739
SonicParanoid	1	1.000	-	-		X1646
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800