DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1129 and tag-335

DIOPT Version :9

Sequence 1:	NP_001189177.2	Gene:	CG1129 / 40599	FlyBaseID:	FBgn0037279	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_502333.2	Gene:	tag-335 / 183400	WormBaseID:	WBGene00016583	Length:	365	Species:	Caenorhabditis elegans

Alignment Length:	365	Identity:	235/365 - (64%)
Similarity:	284/365 - (77%)	Gaps:	8/365 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RALILVGGYGTRLRPLTLSTPKPLVEFANKPILLHQLEALVDAGCRQVILAVSYRAEQMEKELKV 76
            :|||||||||||||||||:.|||||||||||::|||:|||.:.|...|:|||||||||:|:|:.|
Worm     2 KALILVGGYGTRLRPLTLTQPKPLVEFANKPMMLHQMEALAEVGVDTVVLAVSYRAEQLEQEMTV 66

  Fly    77 EAKKLGVELIFSHETEPLGTAGPLALAKTILAASSEPFFVLNSDVICDFPFKQLVQFHCNHGKEG 141
            .|.:|||:||||.|.||||||||||||:..|...: |||||||||||||||||:|:||.||||||
Worm    67 HADRLGVKLIFSLEEEPLGTAGPLALARKHLEGDA-PFFVLNSDVICDFPFKQMVEFHKNHGKEG 130

  Fly   142 TIVVTKVEEPSKYGVVLYDEN-GCIKNFIEKPQEFVSNKINAGIYIFNPSVLDRIEVKPTSIEKE 205
            ||.|||||||||||||::|:: |.|.:|:|||||:|.||||||:|||:..:||||.:||||||||
Worm   131 TIAVTKVEEPSKYGVVVFDQDKGKIDDFVEKPQEYVGNKINAGLYIFSSKILDRIPLKPTSIEKE 195

  Fly   206 VFPEMTQQQELYAMDLTGFWMDIGQPKDFLTGMCLYLSSLRQKQSPKLYTGPG------VVGNVL 264
            :||||.....|||..|.|||||:|||||||.||.|:|:.....:|.||.||..      :.|||:
Worm   196 IFPEMAFSGNLYAFVLPGFWMDVGQPKDFLKGMSLFLNHCHTTKSDKLETGSNIHPTATIRGNVM 260

  Fly   265 VDPTAKIGEGCRIGPNVTIGPDVVIEDGVCIKRSTILKGAIVRSHSWLDSCIVGWRSTVGRWVRI 329
            |||:|.:||.|.|||:|.|||.|.||.||.|..||||..:.:.::||:...|||.:..:|.||||
Worm   261 VDPSATVGENCVIGPDVVIGPRVKIEGGVRILHSTILSDSSIGNYSWVSGSIVGRKCHIGSWVRI 325

  Fly   330 EGITVLGEDVIVKDELYINGGQVLPHKSIAASVPEPQIIM 369
            |.|.|:|:||:||||||:||..||||||||.:||...|||
Worm   326 ENICVIGDDVVVKDELYLNGASVLPHKSIAVNVPSKDIIM 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1129	NP_001189177.2	GCD1	12..361	CDD:224129	230/355 (65%)
		M1P_guanylylT_B_like_N	12..242	CDD:133047	165/230 (72%)
		LbetaH	264..343	CDD:294107	41/78 (53%)
tag-335	NP_502333.2	GCD1	1..354	CDD:224129	227/352 (64%)
		M1P_guanylylT_B_like_N	1..232	CDD:133047	165/230 (72%)
		LbetaH	260..339	CDD:294107	41/78 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158268
Domainoid	1	1.000	329	1.000	Domainoid score	I624
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5578
Inparanoid	1	1.050	465	1.000	Inparanoid score	I860
Isobase	1	0.950	-	0	Normalized mean entropy	S1422
OMA	1	1.010	-	-		QHG61084
OrthoDB	1	1.010	-	-		D336231at33208
OrthoFinder	1	1.000	-	-		FOG0000664
OrthoInspector	1	1.000	-	-		oto20205
orthoMCL	1	0.900	-	-		OOG6_100460
Panther	1	1.100	-	-	LDO	PTHR22572
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R739
SonicParanoid	1	1.000	-	-		X1646
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750